Phase 1 Interaction Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1Phase 2

Opioid Drug Interaction Study

Drug Kineticsdrug interactions
Shanna Babalonis, PhD25 enrolled1 locationNCT06757140
Recruiting
Phase 1

A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity

ObesityOverweightDrug Interaction+1 more
Pfizer20 enrolled1 locationNCT07508241
Recruiting
Phase 1

Drug-Drug Interaction Study of ABP-671 in Gout Patients

GoutGout ChronicDDI (Drug-Drug Interaction)
Atom Therapeutics Co., Ltd20 enrolled1 locationNCT07367971
Recruiting
Phase 1

The Effect of Losartan on Cephalexin

HealthyPossible Interaction Between Losartan and Cephalexin
Aleksi Tornio12 enrolled1 locationNCT07300670
Recruiting
Phase 1

Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination

Healthy VolunteerSafetyPharmacokinetics+2 more
Basilea Pharmaceutica46 enrolled1 locationNCT06733675
Recruiting
Phase 1

to Evaluate the Safety and the Pharmacokinetic and Pharmacodynamic Interactions Between JP-1366 and Clopidogrel, Aspirin, Atorvastatin and Apixaban

Drug-Drug Interaction (DDI)
Onconic Therapeutics Inc.96 enrolled1 locationNCT07265466
Recruiting
Phase 1

Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy

Genetic PredispositionDystoniaPediatric Disorder+5 more
Children's Mercy Hospital Kansas City40 enrolled1 locationNCT06554288
Recruiting
Phase 1Phase 2

Vaginal Microbiome Seeding and Health Outcomes in Cesarean-delivered Neonates.

Intestinal microbiomeMicrobiotaGastrointestinal Microbiome+3 more
National Institute of Allergy and Infectious Diseases (NIAID)600 enrolled1 locationNCT03298334
Completed
Phase 1

Interactions between herbal medicines and the anticoagulant warfarin

Drug interactions of warfarin with herbal medicines in healthy male subjects. Relevant to Stroke prevention and people receiving warfarin
Prof Andrew McLachlan60 enrolled1 locationACTRN12607000054415