Phase 1 Ischemic Clinical Trials
23 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 23 trials
Recruiting
Phase 1Phase 2
A Study of ASP2246 for People Who Have Movement Problems Caused by Brain Injury After a Stroke
Chronic Ischemic Stroke
Astellas Pharma Inc84 enrolled2 locationsNCT07318714
Recruiting
Phase 1Phase 2
Human Placenta-derived 3D Mesenchymal Stem Cells(Guojianqingke)
Acute Ischemic Stroke
Chinese PLA General Hospital24 enrolled1 locationNCT07635758
Recruiting
Phase 1
Anisodine Hydrobromide for Patients With Acute Ischemic Stroke Undergoing Endovascular Therapy (HEAL)
Acute Ischemic Stroke
Capital Medical University92 enrolled2 locationsNCT07513233
Recruiting
Phase 1
Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)
Open-angle Glaucoma (OAG)NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)
Life Biosciences Inc.18 enrolled4 locationsNCT07290244
Recruiting
Phase 1
Dose Optimization of Caffeine for HIE
Hypoxic-ischemic encephalopathy.
University of North Carolina, Chapel Hill16 enrolled2 locationsNCT06448780
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LWP779 in Healthy Participants
Ischemic Stroke
Longwood Pharmaceuticals (Hangzhou) Co., Ltd.76 enrolled1 locationNCT07371455
Recruiting
Phase 1
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
chronic strokeStrokeIschemic Stroke+9 more
Johns Hopkins University20 enrolled1 locationNCT07053917
Recruiting
Phase 1Phase 2
A Study of the Safety, Tolerability and Preliminary Efficacy of B2065 in Patients With Acute Ischemic Stroke.
Acute Ischemic Stroke
Tasly Pharmaceutical Group Co., Ltd54 enrolled1 locationNCT07371624
Recruiting
Phase 1
The Safety and Efficacy of NouvSoma001 in Ischemic Stroke
Ischemic Stroke
Wei Wang69 enrolled1 locationNCT06612710
Recruiting
Phase 1Phase 2
A Phase I/II Clinical Trial of Intramyocardial Injection of HucMSCs for the Treatment of Chronic Heart Failure
Chronic Heart FailureCoronary Artery Bypass Grafting (CABG)Chronic Ischemic Cardiomyopathy
Tasly Pharmaceutical Group Co., Ltd51 enrolled4 locationsNCT07265349
Recruiting
Phase 1Phase 2
The Effect of GD-iExo-003 in Acute Ischemic Stroke
Acute Ischemic Stroke
Xuanwu Hospital, Beijing29 enrolled1 locationNCT06138210
Recruiting
Phase 1Phase 2
Qingre Huatan Formula for the Prevention of Early Neurological Deterioration in Acute Ischemic Stroke
Acute Ischemic Stroke
Dongzhimen Hospital, Beijing72 enrolled1 locationNCT06857487
Recruiting
Phase 1Phase 2
Accelerated rTMS vs. Sham for Stroke Apathy
StrokeMotivationApathy+4 more
Medical University of South Carolina40 enrolled1 locationNCT07113067
Recruiting
Phase 1
Human Embryonic Stem Cell-Derived Cardiomyocyte Therapy for Chronic Ischemic Left Ventricular Dysfunction
Chronic Ischemic Left Ventricular Dysfunction
Joseph C. Wu18 enrolled1 locationNCT05068674
Recruiting
Phase 1Phase 2
Verapamil for Neuroprotection in Stroke
Ischemic Stroke
Global Neurosciences Institute60 enrolled3 locationsNCT03347786
Recruiting
Phase 1
Study on Hibernation-like Therapy Based on Mechanical Thrombectomy
Acute Ischemic Stroke
Capital Medical University32 enrolled1 locationNCT06663631
Recruiting
Phase 1
Role of Citicoline in Treatment of Neonates With Hypoxic Ischemic Encephalopathy
Hypoxic Ischemic Encephalopathy of Newborn
Armed Forces Hospital, Pakistan200 enrolled1 locationNCT06522581
Recruiting
Phase 1
Intra-Arterial Neuroprotective Agents and Cold Saline in Ischemic Stroke Intervention
Stroke, Ischemic
Northwell Health24 enrolled1 locationNCT05032781
Recruiting
Phase 1
Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on DA414
Ischemic Stroke
Chendu DIAO Nine Hong Pharmaceutical Factory82 enrolled1 locationNCT06525168
Completed
Phase 1
A Phase 1 study to evaluate Safety, Tolerability and Pharmacokinetics of LMR-123 in Healthy Subjects
Acute Ischemic Stroke
Australia Medical Industries Pty Ltd.52 enrolled1 locationACTRN12619001609145