Phase 3 Ischemic Clinical Trials
82 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 82 trials
Recruiting
Phase 3
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
Acute Ischemic StrokeCerebral Stroke
Pharmazz, Inc.514 enrolled55 locationsNCT05691244
Recruiting
Phase 3
Single Bolus Non-immunogenic Staphylokinase in Patients With Acute Ischemic Stroke Within 4.5-24 Hours of Symptom Onset
Ischemic Stroke, Acute
Supergene, LLC990 enrolled15 locationsNCT07324837
Recruiting
Phase 3
A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well
Acute Ischemic Stroke
Boehringer Ingelheim1,325 enrolled242 locationsNCT07361302
Recruiting
Phase 2Phase 3
Minocycline After Successful Endovascular Thrombectomy Recanalization in Acute Anterior Circulation Large Vessel Occlusion (ATTRACTION-MINOA)
Acute Ischemic StrokeMinocyclineAnterior Circulation Brain Infarction+2 more
Xiang Luo860 enrolled1 locationNCT07594314
Recruiting
Phase 3
Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis
Acute Ischemic StrokeBrain StrokeStenting Treatment
ProMedica Health System342 enrolled1 locationNCT07356284
Recruiting
Phase 2Phase 3
Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP)
Acute Ischemic StrokeMinocyclineArterial Occlusion+2 more
Xiang Luo234 enrolled1 locationNCT07594301
Recruiting
Phase 3
Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE
Atrial FibrillationAcute Ischemic Stroke
Universitätsklinikum Hamburg-Eppendorf1,746 enrolled1 locationNCT05293080
Recruiting
Phase 2Phase 3
Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke
Central Nervous System DiseasesCerebrovascular DisordersIschemic Stroke, Acute+1 more
University of Melbourne462 enrolled12 locationsNCT05892510
Recruiting
Phase 3
Precision Antiplatelet Therapy Guided by Platelet Aggregation Function in Patients With Acute Ischemic STROKE
Acute Ischemic StrokeClopidogrel Resistance
Sichuan Provincial People's Hospital5,138 enrolled1 locationNCT06853535
Recruiting
Phase 3
Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Anterior Circulation Large Vessel Occlusion Stroke -2
Acute Ischemic Stroke
Capital Medical University692 enrolled53 locationsNCT07263776
Recruiting
Phase 3
Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Posterior Circulation Large Vessel Occlusion Stroke
Ischemic Stroke
Capital Medical University348 enrolled13 locationsNCT07509645
Recruiting
Phase 3
Intra-arterial Tenecteplase for Acute Medium Vessel Occlusion Stroke
Ischemic StrokeMedium Vessel OcclusionEndovascular Treatment+1 more
Beijing Tiantan Hospital488 enrolled1 locationNCT07357987
Recruiting
Phase 2Phase 3
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
StrokeAcute StrokeIschemic Stroke
DiaMedica Therapeutics Inc728 enrolled66 locationsNCT05065216
Recruiting
Phase 3
Concomitant Use of Clopidogrel With Atorvastatin or Rosuvastatin in Patients With Small Vessel Stroke
Ischemic Stroke
Kafrelsheikh University600 enrolled1 locationNCT06358313
Recruiting
Phase 3
OPtimizing REperfusion by Intra-Arterial ThRomboLysis as Adjunct to Endovascular Treatment for Medium Vessel Occlusion
Acute Ischemic Stroke
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University530 enrolled1 locationNCT07137832
Recruiting
Phase 3
Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2
Acute Ischemic Stroke
Capital Medical University1,192 enrolled12 locationsNCT07263308
Recruiting
Phase 3
A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
Ischemic Stroke; Ischemic Attack, Transient
Janssen Research & Development, LLC15,000 enrolled880 locationsNCT05702034
Recruiting
Phase 3
Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke
Stroke, IschemicDrug EffectStroke, Acute+1 more
Xuanwu Hospital, Beijing850 enrolled1 locationNCT06658197
Recruiting
Phase 3
Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Tenecteplase in Medium Vessel Occlusion (MeVO) for Acute Ischemic Stroke
Stroke, IschemicMedium Vessel Occlusions
Beijing Tiantan Hospital596 enrolled7 locationsNCT07047014
Recruiting
Phase 3
PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years
Cryptogenic Ischemic StrokePatent foramen ovale
Assistance Publique - Hôpitaux de Paris792 enrolled42 locationsNCT05387954