Phase 1 ITP Clinical Trials

12 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 112 of 12 trials

Recruiting
Phase 1Phase 2

A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia

Immune Thrombocytopenia (ITP)
Eli Lilly and Company58 enrolled45 locationsNCT06721013
Recruiting
Phase 1

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Antiphospholipid Syndrome (APS)Immune-mediated Necrotizing Myopathy (IMNM)Immune Thrombocytopenia (ITP)+3 more
Chugai Pharmaceutical144 enrolled69 locationsNCT06371417
Recruiting
Phase 1Phase 2

A Phase 1b/2a Study of Budoprutug in Subjects With Immune Thrombocytopenia (ITP)

ITPImmune Thrombocytopenia (ITP)Monoclonal+2 more
Climb Bio, Inc.24 enrolled20 locationsNCT07043946
Recruiting
Phase 1

Study of PN20 in Adult Patients With Primary Immune Thrombocytopenia (ITP)

Primary Immune Thrombocytopenia (ITP)
Chongqing Peg-Bio Biopharm Co., Ltd.12 enrolled5 locationsNCT06880081
Recruiting
Phase 1Phase 2

A Phase Ib/II Clinical Trial of Multiple Doses of STSA-1301 Subcutaneous Injection in Healthy Subjects and Patients With Immune Thrombocytopenia (ITP)

Primary Immune Thrombocytopenia (ITP)
Jiangsu BioJeTay Biotechnology Co., Ltd.56 enrolled7 locationsNCT06929299
Recruiting
Phase 1

CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapse/Refractory Autoimmune Diseases

ANCA Associated Vasculitis (AAV)SLE - Systemic Lupus ErythematosusSSc-Systemic Sclerosis+3 more
Institute of Hematology & Blood Diseases Hospital, China12 enrolled1 locationNCT07315087
Recruiting
Phase 1Phase 2

A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia

Autoimmune Hemolytic AnemiaEvans SyndromeAutoimmune Cytopenia+1 more
Keymed Biosciences Co.Ltd158 enrolled3 locationsNCT07175493
Recruiting
Phase 1

OM336 in Autoimmune Cytopenias

ITP - Immune ThrombocytopeniaAIHA - Warm Autoimmune Hemolytic AnemiaAIHA - Cold Autoimmune Hemolytic Anemia
Ouro Medicines32 enrolled3 locationsNCT07083960
Recruiting
Phase 1Phase 2

A Phase 1/2 Study of ESG206 in Patients With Primary Immune Thrombocytopenia

Immune Thrombocytopenia (ITP)
Shanghai Escugen Biotechnology Co., Ltd84 enrolled1 locationNCT06853444
Recruiting
Phase 1

A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus

Lupus Nephritis (LN)Immune Thrombocytopenia (ITP)
China Immunotech (Beijing) Biotechnology Co., Ltd.36 enrolled1 locationNCT06943937
Recruiting
Phase 1Phase 2

Efficacy and Safety of CAR-T Cells Therapy for Chronic or Refractory Primary Immune Thrombocytopenia (ITP)

ITP - Immune Thrombocytopenia
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China10 enrolled1 locationNCT06352281
Terminated
Phase 1

A Phase I Open-Label, Single Dose, Dose Escalation Study of KB002, a Chimeric Monoclonal Antibody Which Binds to GM-CSF (Granulocyte Macrophage Colony Stimulating Factor), in Patients with Chronic Idiopathic Thrombocytopenia Purpura (ITP)

Idiopathic Thrombocytopenia Purpura (ITP)
KaloBios Pharmaceuticals Inc27 enrolled1 locationACTRN12606000459527