Phase 1 Kidney Transplant Clinical Trials
15 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–15 of 15 trials
Recruiting
Phase 1Phase 2
Immunological Reset to Enable Access to Hla-compatible Kidney Transplantation in Highly Sensitized Patients (RESET)
Kidney TransplantationKidney Failure, ChronicAlloimmunization+3 more
Hospital Universitari Vall d'Hebron Research Institute10 enrolled1 locationNCT07607197
Recruiting
Phase 1Phase 2
Study to Evaluate the Safety and Efficacy of the GGTA1 KO Thymokidney in Patients With ESRD
Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled1 locationNCT07224763
Recruiting
Phase 1
Treatment of Antibody-Mediated Rejection (ABMR) With CarBel
Kidney Transplant Rejection
National Institute of Allergy and Infectious Diseases (NIAID)25 enrolled10 locationsNCT06918990
Recruiting
Phase 1
CAR-T Cell Therapy for Desensitization in Kidney Transplantation
Kidney TransplantKidney FailureEnd Stage Renal Failure on Dialysis
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled3 locationsNCT06056102
Recruiting
Phase 1Phase 2
Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor
Kidney TransplantToleranceRenal Transplant Rejection
Jeffrey Veale, MD15 enrolled1 locationNCT03707262
Recruiting
Phase 1
Eight-Treg Study:Trial of Adoptive Immunotherapy With Autologous ex Vivo Expanded Regulatory CD8+ T Cells in Living Donor Kidney Transplant Recipients
Kidney Transplantation
Nantes University Hospital9 enrolled1 locationNCT06777719
Recruiting
Phase 1Phase 2
Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD
Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled2 locationsNCT06878560
Recruiting
Phase 1Phase 2
The Effects of Vonoprazan Fumarate on DGF Incidence in DD Kidney Transplant Recipients
Kidney TransplantationDelayed Graft Function
First Affiliated Hospital of Chongqing Medical University47 enrolled2 locationsNCT07275632
Recruiting
Phase 1
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
Chronic Kidney DiseasesEnd-stage Kidney DiseaseKidney Transplant Failure and Rejection+1 more
University of California, Los Angeles10 enrolled1 locationNCT05525507
Recruiting
Phase 1Phase 2
CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients
Kidney Transplant; ComplicationsCMV
University of Minnesota30 enrolled1 locationNCT07096453
Recruiting
Phase 1
Adipose-derived MSC to Treat Rejection in Kidney Transplant Recipients
Kidney Transplant
Mayo Clinic12 enrolled1 locationNCT05456243
Recruiting
Phase 1Phase 2
CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk
Kidney FailureEnd Stage Renal DiseaseKidney Tumor+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053462
Recruiting
Phase 1Phase 2
Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant
Prevention of Rejection in Kidney Transplant
Eledon Pharmaceuticals48 enrolled9 locationsNCT05027906
Completed
Phase 1
Impact of perfusion with Methylene Blue on perioperative bleeding in simultaneous pancreas kidney transplant recipients
Intraoperative BleedingSimultaneous Pancreas and Kidney Transplantation
Westmead Hospital50 enrolled1 locationACTRN12621000985886
Recruiting
Phase 1
Mesenchymal Stem Cells (MSC) for the amelioration of ischaemia-reperfusion injury (IRI) after deceased donor renal transplantation, a phase 1 pilot study
Ischaemia reperfusion injuryKidney Transplantation
Royal Perth Hospital10 enrolled1 locationACTRN12615000678594