Phase 1 Kidney Transplant Clinical Trials

11 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 111 of 11 trials

Recruiting
Phase 1

Eight-Treg Study:Trial of Adoptive Immunotherapy With Autologous ex Vivo Expanded Regulatory CD8+ T Cells in Living Donor Kidney Transplant Recipients

Kidney Transplantation
Nantes University Hospital9 enrolled1 locationNCT06777719
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD

Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled2 locationsNCT06878560
Recruiting
Phase 1Phase 2

The Effects of Vonoprazan Fumarate on DGF Incidence in DD Kidney Transplant Recipients

Kidney TransplantationDelayed Graft Function
First Affiliated Hospital of Chongqing Medical University47 enrolled2 locationsNCT07275632
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Efficacy of the GGTA1 KO Thymokidney in Patients With ESRD

Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled1 locationNCT07224763
Recruiting
Phase 1

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

Kidney TransplantKidney FailureEnd Stage Renal Failure on Dialysis
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled3 locationsNCT06056102
Recruiting
Phase 1Phase 2

Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor

Kidney TransplantToleranceRenal Transplant Rejection
Jeffrey Veale, MD15 enrolled1 locationNCT03707262
Recruiting
Phase 1Phase 2

CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients

Kidney Transplant; ComplicationsCMV
University of Minnesota30 enrolled1 locationNCT07096453
Recruiting
Phase 1

Adipose-derived MSC to Treat Rejection in Kidney Transplant Recipients

Kidney Transplant
Mayo Clinic12 enrolled1 locationNCT05456243
Recruiting
Phase 1Phase 2

Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant

Prevention of Rejection in Kidney Transplant
Eledon Pharmaceuticals48 enrolled9 locationsNCT05027906
Completed
Phase 1

Impact of perfusion with Methylene Blue on perioperative bleeding in simultaneous pancreas kidney transplant recipients

Intraoperative BleedingSimultaneous Pancreas and Kidney Transplantation
Westmead Hospital50 enrolled1 locationACTRN12621000985886
Recruiting
Phase 1

Mesenchymal Stem Cells (MSC) for the amelioration of ischaemia-reperfusion injury (IRI) after deceased donor renal transplantation, a phase 1 pilot study

Ischaemia reperfusion injuryKidney Transplantation
Royal Perth Hospital10 enrolled1 locationACTRN12615000678594