Phase 3 Knee Clinical Trials
42 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 42 trials
Recruiting
Phase 3
Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain
Osteoarthritis Knee Pain
Saol Therapeutics Inc150 enrolled20 locationsNCT07226258
Recruiting
Phase 3
Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
Knee Cartilage Defects
Medipost, Inc.300 enrolled16 locationsNCT07339111
Recruiting
Phase 3
A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.
Osteoarthritis, Knee
Paradigm Biopharmaceuticals Ltd.466 enrolled56 locationsNCT06917404
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients
Knee Osteoarthritis
Doron Therapeutics Inc.260 enrolled17 locationsNCT07219771
Recruiting
Phase 3
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
ObesityKnee osteoarthritis (OA)
Novo Nordisk A/S400 enrolled82 locationsNCT07481630
Recruiting
Phase 3
Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN
Total knee replacement surgeryPost Operative Pain
Icahn School of Medicine at Mount Sinai235 enrolled1 locationNCT07548385
Recruiting
Phase 2Phase 3
An Open-Label, Double-Treatment Group Study to Evaluate the Efficacy and Safety of Human Allogeneic Bone-Marrow- Derived Mesenchymal Stromal Cell Product StromaForte Compared With Hyaluronic Acid for the Treatment of Knee Osteoarthritis
Knee Arthritis, Osteoarthritis
Cellcolabs Clinical SPV Limited140 enrolled1 locationNCT07542808
Recruiting
Phase 3
Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children
Musculoskeletal injuryPediatricsSprain and Strain of Ankle+2 more
University of Calgary60 enrolled2 locationsNCT07145645
Recruiting
Phase 3
Metformin Safety and Efficacy in Osteoarthritis.
Osteo Arthritis Knee
Mostafa Bahaa70 enrolled1 locationNCT06231758
Recruiting
Phase 3
Probiotic Supplements in Osteoarthritis
Osteoarthritis, Knee
Beni-Suef University146 enrolled1 locationNCT07364578
Recruiting
Phase 3
Amniotic Suspension Allograft Injection for Knee Osteoarthritis
OsteoarthritisKnee
Chang Gung Memorial Hospital160 enrolled2 locationsNCT06704893
Recruiting
Phase 3
Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans
Osteoarthritis, Knee
VA Office of Research and Development254 enrolled5 locationsNCT06488144
Recruiting
Phase 3
Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine
Nerve BlockAnesthesia, SpinalArthroplasties, Knee Replacement+1 more
University of Toronto50 enrolled1 locationNCT07050277
Recruiting
Phase 2Phase 3
Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA
Osteoarthritis, Knee
University Health Network, Toronto148 enrolled2 locationsNCT05517434
Recruiting
Phase 3
A Phase III Study of CLS2901C in Patients With Osteoarthritis of the Knee
Osteoarthritis of the knee
CellSeed Inc.96 enrolled6 locationsNCT06549686
Recruiting
Phase 3
Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty
Pain, PostoperativeTotal Knee ArthroplastyLiposomal Bupivacaine+2 more
The University of Hong Kong177 enrolled1 locationNCT06740214
Recruiting
Phase 2Phase 3
Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis
Knee arthritis
NYU Langone Health100 enrolled1 locationNCT05020028
Recruiting
Phase 2Phase 3
A Phase 2b/3a Study to Evaluate the Efficacy and Safety of JointStem in Patients Diagnosed as Knee Osteoarthritis
Osteoarthritis, Knee
Nature Cell Co. Ltd.140 enrolled9 locationsNCT04368806
Recruiting
Phase 3
Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis
Knee Osteoarthritis
Wuxi Cellular Biopharmaceutical Group Ltd.520 enrolled2 locationsNCT06570291
Recruiting
Phase 2Phase 3
Photobiomodulation in Chronic Knee Pain in Patients Who Are in PreRehabilitation for Bariatric Surgery
Chronic Knee PainObesity, Morbid
University of Nove de Julho62 enrolled1 locationNCT05816798