Phase 2 Langerhans Cell Histiocytosis Clinical Trials
8 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–8 of 8 trials
Recruiting
Phase 2
A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis
Recurrent Langerhans Cell HistiocytosisRefractory Langerhans Cell Histiocytosis
National Cancer Institute (NCI)48 enrolled117 locationsNCT05828069
Recruiting
Phase 2
Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib
Langerhans Cell Histiocytosis
Cook Children's Health Care System75 enrolled1 locationNCT06582745
Recruiting
Phase 2
Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH
Langerhans Cell Histiocytosis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences50 enrolled1 locationNCT07187193
Recruiting
Phase 2
Mirdametinib in Histiocytic Disorders
Histiocytic DisordersRosai-Dorfman Disease (RDD)Langerhans Cell Histiocytosis (LCH)+1 more
Children's Hospital Medical Center, Cincinnati40 enrolled1 locationNCT06153173
Recruiting
Phase 2
Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children
Langerhans Cell Histiocytosis (LCH)
West China Second University Hospital20 enrolled1 locationNCT07022834
Recruiting
Phase 2Phase 3
LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
Langerhans Cell Histiocytosis
North American Consortium for Histiocytosis1,400 enrolled42 locationsNCT02205762
Recruiting
Phase 2
To Evaluate the Efficacy, Safety, and PK Characteristics of FCN-159 in Pediatric Patients With Refractory/Recurrent LCH
Langerhans Cell HistiocytosisLCH
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.56 enrolled11 locationsNCT05997602
Recruiting
Phase 2
Oral Prednisone in Treating LCH of Bone in Childhood and Adolescence
Langerhans Cell Histiocytosis of Bone
Shanghai Changzheng Hospital118 enrolled1 locationNCT06078969