Left Atrial Appendage Closure Clinical Trials

6 recruiting

Left Atrial Appendage Closure Trials at a Glance

8 actively recruiting trials for left atrial appendage closure are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Basel, Bunkyo-ku, and Chiyoda-ku. Lead sponsors running left atrial appendage closure studies include Baylor Research Institute, Boston Scientific Corporation, and Abbott Medical Devices.

Browse left atrial appendage closure trials by phase

About Left Atrial Appendage Closure Clinical Trials

Looking for clinical trials for Left Atrial Appendage Closure? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Left Atrial Appendage Closure trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Left Atrial Appendage Closure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting
Not Applicable

Intracardiac Versus Transesophageal Echocardiographic Guidance for Left Atrial Appendage Occlusion

Left Atrial Appendage Closure
Baylor Research Institute444 enrolled1 locationNCT06348394
Recruiting
Not Applicable

WATCHMAN FLX Pro European Registry

Left Atrial Appendage ClosureNon-valvular Atrial Fibrillation (AF)
Boston Scientific Corporation1,000 enrolled7 locationsNCT07262255
Recruiting

Frailty in Patient Undergoing Percutaneous Left Atrial Appendage Closure.

FrailtyTranscatheter Left Atrial Appendage Closure
Josep Rodes-Cabau500 enrolled1 locationNCT05257954
Recruiting
Not Applicable

Agilis RF TSP Early Feasibility Study

Left Atrial Appendage ClosureCardiac Arrythmias
Abbott Medical Devices20 enrolled2 locationsNCT07361445
Recruiting
Phase 4

Non-antithrombotic Versus. Single Antiplatelet Therapy Following Left Atrial Appendage Closure

Left Atrial Appendage ClosureAspirinNonvalvular Atrial Fibrillation+2 more
OCEAN-SHD Study Group500 enrolled21 locationsNCT07125417
Recruiting
Not Applicable

Oral Anticoagulation Versus Left Atrial Appendage Occlusion Added to Direct Oral Anticoagulation in Patients with Stroke Despite Oral

Left Atrial Appendage Closure
Hospital Clinic of Barcelona380 enrolled1 locationNCT06869811
Recruiting

Austrian Left Atrial Appendage Closure Registry

Atrial FibrillationLeft Atrial Appendage Closure
Medical University of Graz200 enrolled1 locationNCT03409159
Recruiting

Coherex WaveCrest Left Atrial Appendage Occlusion Study A multi-center study to evaluate the safety and efficacy of the Coherex WaveCrest Left Atrial Appendage Occlusion System

Non-valvular atrial fibrillation in anticoagulation indicated and contraindicated patient and the effect of implantation of a left atrial appendage closure system.
Coherex Medical Inc.200 enrolled4 locationsACTRN12610000921088