Phase 3 Leg Clinical Trials
19 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–19 of 19 trials
Recruiting
Phase 3
Cellulitis Optimal Antibiotic Treatment
Cellulitis of Leg
University of Southampton334 enrolled1 locationNCT05584007
Recruiting
Phase 2Phase 3
A Self-Controlled Study on the Treatment of Restless Legs Syndrome in Uremia With Dipyridamole
Restless Leg Syndrome Due to Uraemia
Yunfeng Xia80 enrolled1 locationNCT07199504
Recruiting
Phase 3
Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.
Hereditary Spastic Paraplegia Type 50
Elpida Therapeutics SPC24 enrolled2 locationsNCT06692712
Recruiting
Phase 3
Efficacy of Early Argipressin in the Management of Intensive Care Patients With Norepinephrine-refractory Vasoplegic Shock
Patients With Norepinephrine-refractory Vasoplegic Shock
Centre Hospitalier Universitaire Dijon390 enrolled1 locationNCT07063680
Recruiting
Phase 3
A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)
Venous Leg Ulcer (VLU)
MediWound Ltd216 enrolled25 locationsNCT06568627
Recruiting
Phase 3
Tissue Repair Gel in Venous Leg Ulcers (US)
WoundsWound HealVenous Ulcer+5 more
TR Therapeutics312 enrolled33 locationsNCT06707090
Recruiting
Phase 3
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
InfectionsInjury LegAmputation+6 more
Major Extremity Trauma Research Consortium250 enrolled13 locationsNCT05699174
Recruiting
Phase 3
Thromboprophylaxis in Lower Limb Immobilisation
ThrombosisInjury Leg
Queen Mary University of London10,044 enrolled3 locationsNCT06370273
Recruiting
Phase 3
Mechanisms of Stimulation for Pain Alleviation
Chronic Neuropathic PainChronic Neuropathic Pain in the Low Back and LegsPeripheral Nerve Stimulation
Stanford University148 enrolled1 locationNCT06741579
Recruiting
Phase 3
Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II
Cardiac SurgeryVasoplegia
Universität Münster1,022 enrolled4 locationsNCT06615102
Recruiting
Phase 3
Tissue Repair Gel in Venous Leg Ulcers in AU/US
WoundWound HealVenous Ulcer+5 more
TR Therapeutics312 enrolled12 locationsNCT06707103
Recruiting
Phase 3
Clemastine Fumarate as Remyelinating Treatment in Internuclear Ophthalmoparesis and Multiple Sclerosis
Multiple SclerosisInternuclear Ophthalmoplegia
Amsterdam UMC, location VUmc80 enrolled1 locationNCT05338450
Completed
Phase 3
Factorial4VLU: Exercise or dilute hypochlorous acid for venous leg ulcers: a factorial randomised trial
Venous leg ulceration
University of Auckland380 enrolled1 locationACTRN12620000116921
Completed
Phase 3
Clinical effectiveness of aspirin as an adjunct to compression therapy in healing chronic venous leg ulcers: a randomised double-blind placebo-controlled trial [the ASPiVLU study]
Venous Leg Ulcer
Monash University268 enrolled6 locationsACTRN12614000293662
Completed
Phase 2Phase 3
Upper limb - Baby Early Action-observation Training: Randomised trial of the effect of infant action observation training on the early development of hand reaching and grasping in healthy infants and in infants with early brain injury.
Venous infarctionAsymmetric brain lesionsCongenital hemiplegia+1 more
Professor Roslyn Boyd72 enrolled1 locationACTRN12611000991910
Terminated
Phase 2Phase 3
A phase II/III study to evaluate the efficacy and safety of MD 920 (Gibberellic Acid and Salt 1:1) in patients with hard to heal chronic venous ulceration
venous leg ulcers
AUS BIO Ltd158 enrolled1 locationACTRN12608000060347
Completed
Phase 2Phase 3
Progressive resistant exercise programme for healing venous leg ulcers
Venous leg ulceration
Principal investigator (Andrew Jull)50 enrolled1 locationACTRN12606000491561
Completed
Phase 3Phase 4
A prospective, randomised controlled trial of auto-titrating Continuous positive airway pressure treatment for Obstructive Sleep Apnoea after acute Quadriplegia
Acute tetraplegia
Institute for Breathing and Sleep150 enrolled2 locationsACTRN12605000799651
Terminated
Phase 3Phase 4
Daily Tenderwet dressings vs QID normal Saline compress as wound debridement agents
Chronic leg ulcers
Fremantle Hospital & Health Service60 enrolled1 locationACTRN12605000180617