Phase 2 Leptomeningeal Disease Clinical Trials

3 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 1–3 of 3 trials

Recruiting

Phase 1Phase 2

Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease

HER2-positive Breast CancerLeptomeningeal DiseaseLeptomeningeal Metastasis

H. Lee Moffitt Cancer Center and Research Institute39 enrolled2 locationsNCT04588545

Recruiting

Phase 2

Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

Metastatic Breast CancerLeptomeningeal Disease

Wake Forest University Health Sciences16 enrolled3 locationsNCT02422641

Recruiting

Phase 2

Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease

HER2-positive Metastatic Breast CancerLeptomeningeal DiseaseLeptomeningeal Metastasis

UNICANCER30 enrolled11 locationsNCT05800275