Phase 3 Leukaemia Clinical Trials

12 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 112 of 12 trials

Recruiting
Phase 2Phase 3

L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML

Acute Myeloid Leukaemia (AML)
Moleculin Biotech, Inc.312 enrolled25 locationsNCT06788756
Not Yet Recruiting
Phase 3

ALLG AMLM29 CAVIAT-R (Chemotherapy and Venetoclax in Acute Myeloid Leukaemia (AML) Trial- Randomised): a multicentre phase III trial investigating venetoclax plus intensive chemotherapy for newly diagnosed AML

Acute Myeloid Leukaemia
Australasian Leukaemia and Lymphoma Group390 enrolled1 locationACTRN12625001003460
Recruiting
Phase 2Phase 3

Intravenous Autologous CD19 CAR-T Cells for R/R B-ALL

Relapsed B Acute Lymphoblastic LeukaemiaRefractory B Acute Lymphoblastic Leukaemia
National University of Malaysia10 enrolled1 locationNCT03937544
Recruiting
Phase 3

MA+AZA Regimen for the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukaemia
Zhongnan Hospital154 enrolled11 locationsNCT06345365
Recruiting
Phase 2Phase 3

Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Acute Lymphoblastic Leukaemia
St. Anna Kinderkrebsforschung1,800 enrolled119 locationsNCT01949129
Recruiting
Phase 3

International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia

Acute Myeloid Leukaemia
University of Birmingham700 enrolled68 locationsNCT02724163
Active
Phase 3

Study of using Cyclophosphamide After Sibling-donor allogeneic stem-cell Transplantation (CAST) in patients with acute leukaemia and myelodysplasia

MyelodysplasiaAcute Leukaemias
Australasian Leukaemia and Lymphoma Group134 enrolled10 locationsACTRN12618000505202
Completed
Phase 3

Phase III Clinical Study of Allogeneic Stem Cell Transplantation with Reduced Conditioning (RICT) versus Best Standard of Care in Acute Myeloid Leukemia (AML) in First Complete Remission

Acute Myeloid Leukaemia
Australasian Leukaemia & Lymphoma Group (ALLG)40 enrolled3 locationsACTRN12614000351617
Completed
Phase 3

The research project is trying to find out if we can improve the results of best available chemotherapy for Chronic Lymphocytic Leukaemia (CLL) by the addition of a new drug called lenalidomide.

Chronic Lymphocytic Leukaemia (CLL)
Australasian Leukaemia and Lymphoma Group (ALLG)192 enrolled1 locationACTRN12610000060044
Completed
Phase 3

Human Papilloma Virus (HPV) Vaccination in Special Risk Groups

Special Risk Groups 1. Paediatric Rheumatalogical Disease 2. Inflammatory Bowel Disease 3. Acute Lymphoblastic Leukaemia 4. Solid Organ Transplant Recipients (kidney and liver) 5. Chronic Renal Disease 6. Bone Marrow Transsplant The response to the HPV vaccine will be studied within these 6 special risk groups.
National Health and Medical Research Council & Clinical Centre of Research Excellence(NHMRC CCRE) in Childhood and Adolescent Immunisation100 enrolled1 locationACTRN12609000571279
Active
Phase 3

Preventing Invasive Pneumococcal Disease in Children & Adolescents with Leukaemia

Immunogenicity of pneumococcal vaccination in children and adolescents newly diagnosed with Leukaemia, with the aim to protect them from invasive pneumococcal disease
NHMRC CCRE in Childhood and Adolescent Immunisation100 enrolled1 locationACTRN12609000515291
Completed
Phase 3

R3: An International Collaborative Trial for Relapsed and Refractory Acute Lymphoblastic Leukaemia (ALL)

relapsed acute lymphoblastic leukaemia in children
University Hospitals of Leicester National Health Service (NHS) Trust300 enrolled1 locationACTRN12608000495325