Leukoplakia Clinical Trials

1 recruiting

Leukoplakia Trials at a Glance

8 actively recruiting trials for leukoplakia are listed on ClinicalTrialsFinder across 6 cities in 4 countries. The largest study group is Phase 2 with 3 trials, with the heaviest enrollment activity in Alexandria, Cairo, and Columbus. Lead sponsors running leukoplakia studies include Cairo University, Jonsson Comprehensive Cancer Center, and Alexandria University.

Browse leukoplakia trials by phase

Treatments under study

About Leukoplakia Clinical Trials

Looking for clinical trials for Leukoplakia? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Leukoplakia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Leukoplakia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting
Phase 2

Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia

Oral Leukoplakia
Cairo University34 enrolled1 locationNCT07387900
Recruiting
Not Applicable

Efficacy of Topical Coenzyme Q10 and Curcumin for Oral Leukoplakia Treatment

Oral Leukoplakia
Alexandria University34 enrolled1 locationNCT07331935
Recruiting
Phase 2

Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

Oral Leukoplakia
University of Minnesota36 enrolled2 locationsNCT05727761
Recruiting
Phase 1

Fenretinide Mucoadhesive Patch: Evaluation of Oral Cancer Prevention Efficacy in Adults With Premalignant Oral Lesions.

Oral LeukoplakiaOral Dysplasia
Ohio State University25 enrolled1 locationNCT07149220
Recruiting
Phase 2

Pembrolizumab in Treating Participants With Leukoplakia

ErythroleukoplakiaLeukoplakiaVerrucous Oral Leukoplakia
Jonsson Comprehensive Cancer Center26 enrolled3 locationsNCT03603223
Recruiting

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography

Oral Squamous Cell CarcinomaOral LeukoplakiaOral Lichen Planus+3 more
University of Palermo200 enrolled1 locationNCT06321003
Recruiting
Not Applicable

Oral Potentially Malignant Disorders: Comparison Between Surgical Treatment and Wait and See Approach

Leukoplakia, Oral
University of Milan310 enrolled2 locationsNCT04858100
Recruiting

Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore

Oral LeukoplakiaOral Leukoplakia of TongueOral Leukoplakia of Gingiva+1 more
University of Erlangen-Nürnberg Medical School500 enrolled1 locationNCT03975322