Phase 4 LN Clinical Trials
24 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 24 trials
Recruiting
Phase 4
Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients
Critical Illness
Scarborough General Hospital3,253 enrolled6 locationsNCT07173855
Recruiting
Phase 4
Immunogenicity and Safety PCV-20 of the Vaccine Administered During an Acute Febrile Illness in Adults
Pneumococcal InfectionsAcute Febrile Illness
Centre Hospitalier Universitaire de Saint Etienne1,052 enrolled24 locationsNCT06822907
Recruiting
Phase 4
CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS
Critical IllnessCritical Care, Intensive CareFluid and Electrolyte Imbalance+2 more
University Hospital, Antwerp640 enrolled4 locationsNCT07189091
Recruiting
Phase 4
Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients
SurgeryMechanical Ventilation ComplicationCritical Illness+3 more
Beijing Shijitan Hospital, Capital Medical University306 enrolled1 locationNCT06575530
Recruiting
Phase 4
Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients
MalnutritionMalnutrition, ChildEssential Fatty Acid Deficiency (EFAD)+1 more
Fresenius Kabi100 enrolled5 locationsNCT06049680
Recruiting
Phase 4
Effectiveness of Interventional Therapy for Non-Flow-Limiting Vulnerable Plaques
Coronary Arterial Disease (CAD)Vulnerable Coronary PlaquesThin-cap fIbroatheroma
Beijing Anzhen Hospital2,190 enrolled1 locationNCT06855537
Recruiting
Phase 4
Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition
Severe Acute MalnutritionMalnutrition, Child
University of California, San Francisco3,000 enrolled1 locationNCT06010719
Recruiting
Phase 4
Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients
Critical IllnessNew Onset Atrial Fibrillation
Dr. Stephanie Sibley200 enrolled4 locationsNCT05829317
Completed
Phase 4
Route of administration of magnesium replacement in the ICU
Critical IllnessHypomagnesemia
Royal Melbourne Hospital330 enrolled1 locationACTRN12623000248662
Not Yet Recruiting
Phase 4
Can N-acetylcysteine (NAC) supplementation enhance altitude training in elite runners?
Altitude induced illnessExercise induced inflammation
Australian Institute of Sport18 enrolled1 locationACTRN12617000427370
Not Yet Recruiting
Phase 4
Can N-acetylcysteine (NAC) supplementation enhance exposure to altitude in well-trained cyclists?
Altitude induced illnessExercise performanceExercise induced inflammation
Australian Institute of Sport12 enrolled1 locationACTRN12617000425392
Completed
Phase 4
The effect of standard versus energy dense feeds on gastric emptying and glucose metabolism in critically ill patients
Critical Illness
Intensive Care Research Unit, Royal Adelaide Hospital25 enrolled1 locationACTRN12617000384358
Active
Phase 4
A single centre nested cohort study investigating the effect of using 0.9 % saline or Plasmalyte 148 as primary fluid therapy on gastrointestinal complications in mechanically ventilated patients with nasogastric enteral nutrition
Mechanical VentilationCritical Illness
Medical Research Institute of New Zealand200 enrolled1 locationACTRN12614000269639
Completed
Phase 4
The effect of routine pantoprazole administration when compared to placebo on gastrointestinal bleeding, ventilator-associated pneumonia and Clostridium difficile infection in enterally-fed mechanically ventilated critically ill patients: A prospective randomised study
Gastrointestinal BleedingCritical Illness
Dr Adam Deane500 enrolled1 locationACTRN12613000807752
Not Yet Recruiting
Phase 3Phase 4
Evaluation of outcomes from correction of vitamin D levels in residential care facility residents
Fracturesthe need of hospitalisationacute illnesses and exacerbation of chronic conditions+1 more
ACT Government Health Directorate250 enrolled1 locationACTRN12611000950965
Active
Phase 4
What is the best way to provide dietetic care to patients admitted to hospital who have been identified as having illness related malnutrition: Which of two current service models benefits patients in the long term?
Illness related malnutrition
Wollongong Hospital240 enrolled1 locationACTRN12611000851965
Not Yet Recruiting
Phase 4
Proof-of-Concept Study of Insulin Glargine as Basal Insulin Support for Recovering Critically Ill Patients
stress diabetes in critical illness
Canterbury District Health Board/Christchurch Hospital60 enrolled1 locationACTRN12610000574044
Not Yet Recruiting
Phase 4
Synergistic effect of Clonidine on sedation requirements in Paediatric Intensive Care (PICU)
sedation in critical illness
Alana Kirkwood120 enrolled1 locationACTRN12610000079044
Not Yet Recruiting
Phase 4
An open trial of a Cognitive Behavioural Therapy (CBT)-based smoking cessation plus Varenicline intervention in people with a psychotic disorder
Smoking cessation in people with a psychotic illness.
Pfizer Australia (Investigator Initiated Grant)15 enrolled1 locationACTRN12609000270213
Not Yet Recruiting
Phase 3Phase 4
Does a moderate dose fish oil intervention improve outcomes in older adults recovering from hip fracture?
Elderly hip fracture patients with malnutrition
Dr Michelle Miller150 enrolled1 locationACTRN12609000241235