RecruitingPhase 4NCT05829317

Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients

Parenteral Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients - a Pilot Feasibility Study


Sponsor

Dr. Stephanie Sibley

Enrollment

200 participants

Start Date

Aug 20, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

A double-blind, multi-centre, randomized, placebo-controlled, feasibility pilot trial in the prevention of new onset atrial fibrillation of critically ill patients admitted to an ICU.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether giving intravenous magnesium to critically ill patients in the ICU can prevent them from developing a new irregular heart rhythm called atrial fibrillation, which is a common and dangerous complication in this setting. **You may be eligible if...** - You are 18 years or older - You have been admitted to an ICU and are receiving breathing support (non-invasive ventilation or a breathing tube expected for more than 24 hours) or are on medications to support your heart or blood pressure - OR you have experienced a cardiac arrest - Your heart is being continuously monitored **You may NOT be eligible if...** - You have already been in the ICU receiving these interventions for more than 18 hours before enrolment - You already have atrial fibrillation - You are on oral or IV amiodarone (a heart rhythm drug) - You are unlikely to survive more than 24 hours, or you are in palliative care - You have had cardiac surgery - You need magnesium for another reason (e.g., preeclampsia or severe asthma) - You are on dialysis - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGMagnesium sulfate

Intravenous Magnesium sulfate

DRUGPlacebo

0.9% NaCl


Locations(4)

St Joseph's Healthcare Hamilton

Hamilton, Ontario, Canada

Kingston Health Sciences Centre

Kingston, Ontario, Canada

The Ottawa Hospital - General Campus

Ottawa, Ontario, Canada

The Ottawa Hospital - Civic Campus

Ottawa, Ontario, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05829317


Related Trials