Phase 1 Lymphoid Leukemia Clinical Trials

6 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 16 of 6 trials

Recruiting
Phase 1Phase 2

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

Acute Lymphoblastic LeukemiaLymphoma, Non-HodgkinB-cell Lymphoma+8 more
National Cancer Institute (NCI)126 enrolled1 locationNCT05442515
Recruiting
Phase 1

UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1

Acute Lymphoblastic LeukemiaAcute Lymphoid Leukemia
University of Colorado, Denver29 enrolled1 locationNCT05535855
Recruiting
Phase 1

A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)

Refractory Acute Lymphoblastic LeukemiaPhiladelphia-Negative ALLPhiladelphia-Positive ALL+3 more
Memorial Sloan Kettering Cancer Center18 enrolled7 locationsNCT06287528
Recruiting
Phase 1Phase 2

Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia

ALL, Childhood B-CellAcute Lymphoid Leukemia RelapseAcute Lymphocytic Leukemia Refractory
University Hospital Tuebingen20 enrolled11 locationsNCT05366218
Recruiting
Phase 1

Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT

Acute Myeloid LeukemiaMyelodysplastic SyndromesMixed Phenotype Acute Leukemia+1 more
Stanford University24 enrolled1 locationNCT06551584
Recruiting
Phase 1Phase 2

Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)

Acute Myeloid LeukemiaMixed Phenotype Acute LeukemiaAcute Lymphoid Leukemia+4 more
University of Florida40 enrolled4 locationsNCT05322850