Malignant Mesothelioma Clinical Trials

9 recruiting

Malignant Mesothelioma Trials at a Glance

9 actively recruiting trials for malignant mesothelioma are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Phase 1 with 6 trials, with the heaviest enrollment activity in Pittsburgh, Beijing, and Chicago. Lead sponsors running malignant mesothelioma studies include David Bartlett, MD, InSilico Medicine Hong Kong Limited, and Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).

Browse malignant mesothelioma trials by phase

Treatments under study

About Malignant Mesothelioma Clinical Trials

Looking for clinical trials for Malignant Mesothelioma? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Malignant Mesothelioma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Malignant Mesothelioma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Phase 2

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Peritoneal Malignant Mesothelioma
National Cancer Institute (NCI)66 enrolled40 locationsNCT05001880
Recruiting
Phase 1

Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors

Pleural Effusion, MalignantMalignant MesotheliomaMalignant Pleural Effusion+1 more
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)10 enrolled1 locationNCT07443020
Recruiting
Phase 1

Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

Advanced Solid TumorMalignant MesotheliomaMetastatic Malignant Solid Tumor
InSilico Medicine Hong Kong Limited100 enrolled10 locationsNCT06566079
Recruiting
Phase 1

Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease

Pleural Effusion, MalignantMalignant MesotheliomaMalignant Pleural Effusion+1 more
David Bartlett, MD10 enrolled1 locationNCT07192900
Recruiting
Phase 2

Brentuximab Vedotin in Treating Patients With CD30+ Malignant Mesothelioma That Cannot Be Removed by Surgery

Malignant MesotheliomaCD30-Positive Neoplastic Cells Present
M.D. Anderson Cancer Center55 enrolled1 locationNCT03007030
Recruiting
Phase 2

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

Malignant MesotheliomaMesotheliomaMesothelioma, Malignant+2 more
Memorial Sloan Kettering Cancer Center64 enrolled13 locationsNCT06057935
Recruiting
Phase 1

A Study of MT027 in Patients with Pleural Malignant Tumors

Malignant Pleural EffusionAdvanced Malignant Solid TumorPleural Metastases+3 more
Suzhou Maximum Bio-tech Co., Ltd.18 enrolled1 locationNCT06726564
Recruiting
Phase 1

Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors

Breast Cancer FemaleColorectal, CancerPancreatic Cancer+4 more
UTC Therapeutics Inc.24 enrolled1 locationNCT06256055
Recruiting
Phase 1

Optimising regulatory T cell depletion with cyclophosphamide in combination with chemotherapy for enhanced anti-tumour immunity in patients with non-small cell lung cancer (NSCLC) and malignant mesothelioma (MM).

Malignant Mesothelioma
Sir Charles Gairdner Hospital33 enrolled1 locationACTRN12609000260224