Phase 2 MASH Clinical Trials

10 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 110 of 10 trials

Recruiting
Phase 2

Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH

MASH - Metabolic Dysfunction-Associated Steatohepatitis
Madrigal Pharmaceuticals, Inc.120 enrolled17 locationsNCT07335601
Recruiting
Phase 2

A Study of Chiglitazar in Patients With Metabolic Dysfunction-associated Steatohepatitis and Type 2 Diabetes Mellitus

MASH - Metabolic Dysfunction-Associated SteatohepatitisT2DM (Type 2 Diabetes Mellitus)
Shanghai Jiao Tong University School of Medicine300 enrolled17 locationsNCT07303803
Recruiting
Phase 2

Digoxin In NASH (CODIN)

MASLDMASH - Metabolic Dysfunction-Associated SteatohepatitisFatty Liver Disease+5 more
Yale University144 enrolled2 locationsNCT06588699
Recruiting
Phase 1Phase 2

Study of TGM-312-SC01 in Healthy Participants and Adults With MASH

Healthy ParticipantsMASH - Metabolic Dysfunction-Associated Steatohepatitis
Tangram Therapeutics Plc99 enrolled1 locationNCT07427680
Recruiting
Phase 2

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

Metabolic dysfunction-associated steatohepatitis (MASH)
Regeneron Pharmaceuticals120 enrolled71 locationsNCT05519475
Recruiting
Phase 2

A Study of CS060380 Tablets in Patients With MASH and Obesity

Metabolic dysfunction-associated steatohepatitis (MASH)Obesity
Cascade Pharmaceuticals, Inc120 enrolled12 locationsNCT07466017
Recruiting
Phase 2

A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)

MASH - Metabolic Dysfunction-Associated Steatohepatitis
Rivus Pharmaceuticals, Inc.180 enrolled31 locationsNCT07491458
Recruiting
Phase 2

A Study of UBT251 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Metabolic dysfunction-associated steatohepatitis (MASH)
The United Bio-Technology (Hengqin) Co., Ltd.156 enrolled1 locationNCT07145151
Recruiting
Phase 2

A Study of IBI362 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Metabolic dysfunction-associated steatohepatitis (MASH)
Innovent Biologics (Suzhou) Co. Ltd.165 enrolled1 locationNCT06937749
Recruiting
Phase 2

A Phase 2a double-blind, randomised, placebo-controlled, parallel group study to evaluate the efficacy, safety, tolerability and pharmacokinetics (PK) of GL0034 in adults with at-risk metabolic dysfunction-associated steatohepatitis (MASH)

Metabolic dysfunction-associated steatohepatitis (MASH)
Sun Pharmaceuticals Ltd60 enrolled1 locationACTRN12625000241437