Phase 2 Melanoma Stage IV Clinical Trials
13 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–13 of 13 trials
Recruiting
Phase 2
Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma
MelanomaAdvanced MelanomaMelanoma Stage IV+1 more
H. Lee Moffitt Cancer Center and Research Institute90 enrolled1 locationNCT06295159
Recruiting
Phase 2
IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients
Melanoma Stage IVInoperable DiseaseMelanoma Stage III
H. Lee Moffitt Cancer Center and Research Institute29 enrolled1 locationNCT04562129
Recruiting
Phase 1Phase 2
Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
Solid TumorMelanoma Stage IV
Georgiamune Inc117 enrolled11 locationsNCT06425926
Recruiting
Phase 1Phase 2
MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma
Metastatic MelanomaMelanoma Stage IVMelanoma Stage III+1 more
Perspective Therapeutics300 enrolled13 locationsNCT05655312
Recruiting
Phase 2
Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma
MelanomaMelanoma Stage IVMelanoma (Skin)+1 more
University of California, Irvine14 enrolled1 locationNCT06771544
Recruiting
Phase 2
Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanoma
Cutaneous MelanomaMelanoma Stage IVMucosal Melanoma
University Health Network, Toronto54 enrolled1 locationNCT06319196
Recruiting
Phase 2
[68Ga]Ga-FAPI Total Body PET/CT for Better and Faster Imaging in Cancer
Malignant Melanoma Stage IV
Barbara Malene Fischer20 enrolled2 locationsNCT07215182
Recruiting
Phase 1Phase 2
Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers
Sarcoma, SynovialSarcoma,Soft TissueMelanoma Stage IV
Hadassah Medical Organization3 enrolled1 locationNCT05296564
Recruiting
Phase 2
Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma
Melanoma Stage IVMelanoma Stage III
University of California, San Francisco25 enrolled2 locationsNCT04598009
Recruiting
Phase 1Phase 2
A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
CancerCutaneous MelanomaMelanoma Stage IV+1 more
Krystal Biotech, Inc.240 enrolled15 locationsNCT05970497
Recruiting
Phase 1Phase 2
FMT to Convert Response to Immunotherapy
Melanoma Stage IVMelanoma Stage III
The Netherlands Cancer Institute24 enrolled1 locationNCT05251389
Recruiting
Phase 2
Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination with Pembrolizumab, in Unresectable Melanoma Patients
Melanoma Stage IVMelanoma Stage III
Philogen S.p.A.162 enrolled1 locationNCT06284590
Recruiting
Phase 2
Adoptive Cell Therapy Following a Non-myeloablative, Lymphodepleting Induction Regimen in Metastatic Melanoma Patients
Malignant Melanoma Stage IV
Sheba Medical Center30 enrolled1 locationNCT03166397