Melanoma Clinical Trials in Boston, Massachusetts

32 recruitingBoston, Massachusetts

Showing 120 of 32 trials

Recruiting
Phase 1

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Melanoma
Pfizer267 enrolled41 locationsNCT05355701
Recruiting
Phase 1

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

MelanomaThyroid CancerGlioma
Pfizer124 enrolled77 locationsNCT05538130
Recruiting
Phase 2Phase 3

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

Unresectable MelanomaCutaneous MelanomaMelanoma (Skin Cancer)+1 more
Linnaeus Therapeutics, Inc.135 enrolled9 locationsNCT06624644
Recruiting
Phase 1

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

Esophageal CancerGastric CancerCervical Cancer+5 more
Genentech, Inc.450 enrolled41 locationsNCT05581004
Recruiting
Phase 2

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Recurrent Mucosal MelanomaMucosal MelanomaAnal Melanoma+14 more
National Cancer Institute (NCI)101 enrolled147 locationsNCT05111574
Recruiting
Phase 2Phase 3

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

Metastatic Uveal Melanoma
Replimune, Inc.280 enrolled33 locationsNCT06581406
Recruiting
Not Applicable

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

MelanomaBreast Cancer, NOSCNS Primary Tumor, NOS+9 more
Eastern Cooperative Oncology Group400 enrolled347 locationsNCT05108298
Recruiting
Not Applicable

Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver

Uveal Melanoma
Massachusetts General Hospital10 enrolled1 locationNCT07364474
Recruiting
Phase 3

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

Uveal MelanomaChoroidal MelanomaIndeterminate Lesions+1 more
Aura Biosciences100 enrolled71 locationsNCT06007690
Recruiting
Phase 3

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

Advanced Melanoma
Immunocore Ltd540 enrolled82 locationsNCT05549297
Recruiting
Phase 1Phase 2

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Ovarian CarcinomaColorectal CarcinomaMelanoma+19 more
Children's Oncology Group147 enrolled21 locationsNCT04851119
Recruiting
Phase 1

ACTengine® IMA203 Combined With mRNA-4203

Cutaneous MelanomaSynovial Sarcoma
Immatics US, Inc.15 enrolled4 locationsNCT06946225
Recruiting
Phase 2

Cryoablation+Ipilimumab+Nivolumab in Melanoma

Metastatic MelanomaSkin Cancer
Massachusetts General Hospital37 enrolled1 locationNCT05779423
Recruiting

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

Bladder CarcinomaEsophageal CarcinomaNon-small Cell Lung Cancer+13 more
Guardant Health, Inc.2,020 enrolled57 locationsNCT05059444
Recruiting
Phase 2

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Non-small Cell Lung CancerMetastatic MelanomaSquamous Cell Carcinoma of the Head and Neck
Iovance Biotherapeutics, Inc.245 enrolled45 locationsNCT03645928
Recruiting
Phase 2

Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients

MelanomaHead and Neck Squamous Cell CarcinomaColo-rectal Cancer
Vyriad, Inc.87 enrolled27 locationsNCT04291105
Recruiting
Phase 1

NeoVax + CDX-301 and Nivolumab or Pembrolizumab in Melanoma

MelanomaMetastatic Melanoma
Dana-Farber Cancer Institute30 enrolled1 locationNCT04930783
Recruiting
Phase 1Phase 2

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

Solid Tumor, AdultCutaneous MelanomaRefractory Cancer+3 more
GV20 Therapeutics365 enrolled13 locationsNCT05669430
Recruiting
Phase 1Phase 2

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

MelanomaCancerSolid Tumor+1 more
Simcha IL-18, Inc.316 enrolled6 locationsNCT04787042
Recruiting
Phase 2

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Breast CancerLung CancerMelanoma+3 more
Dana-Farber Cancer Institute134 enrolled2 locationsNCT04899908