Metastatic Clear Cell Renal Cell Carcinoma Clinical Trials

10 recruiting

Metastatic Clear Cell Renal Cell Carcinoma Trials at a Glance

11 actively recruiting trials for metastatic clear cell renal cell carcinoma are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Phase 1 with 6 trials, with the heaviest enrollment activity in Duarte, Cleveland, and Jacksonville. Lead sponsors running metastatic clear cell renal cell carcinoma studies include Beijing Biotech, City of Hope Medical Center, and Arcus Biosciences, Inc..

Browse metastatic clear cell renal cell carcinoma trials by phase

Treatments under study

About Metastatic Clear Cell Renal Cell Carcinoma Clinical Trials

Looking for clinical trials for Metastatic Clear Cell Renal Cell Carcinoma? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Metastatic Clear Cell Renal Cell Carcinoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Metastatic Clear Cell Renal Cell Carcinoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Phase 3

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

Metastatic Clear Cell Renal Cell CarcinomaAdvanced Clear Cell Renal Cell Carcinoma
Arcus Biosciences, Inc.720 enrolled44 locationsNCT07011719
Recruiting
Phase 2

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

Stage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8Metastatic Clear Cell Renal Cell Carcinoma+1 more
Vanderbilt-Ingram Cancer Center54 enrolled6 locationsNCT05361720
Recruiting
Phase 1Phase 2

Dual-target CD70/CAIX CAR-NK Cells for Advanced Clear Cell Renal Cell Carcinoma

Advanced or Metastatic Clear Cell Renal Cell Carcinoma
Beijing Biotech36 enrolled1 locationNCT07551349
Recruiting

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

Metastatic Cervical CarcinomaMetastatic Endometrial CarcinomaMetastatic Lung Non-Small Cell Carcinoma+24 more
Mayo Clinic324 enrolled3 locationsNCT06349642
Recruiting
Phase 1

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

Stage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8Metastatic Clear Cell Renal Cell Carcinoma+3 more
City of Hope Medical Center33 enrolled2 locationsNCT07128680
Recruiting
Phase 1

Effects of Belzutifan on 89Zr-DFO-girentuximab PET Uptake in Patients With Renal Cell Carcinoma (RCC)

Metastatic Clear Cell Renal Cell Carcinoma
NYU Langone Health12 enrolled1 locationNCT07179770
Recruiting
Phase 1Phase 2

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

Stage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8Metastatic Clear Cell Renal Cell Carcinoma+3 more
University of Michigan Rogel Cancer Center55 enrolled1 locationNCT06866262
Recruiting
Phase 3

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

Metastatic Renal Cell CarcinomaStage IV Renal Cell Cancer AJCC v8Metastatic Clear Cell Renal Cell Carcinoma
SWOG Cancer Research Network364 enrolled387 locationsNCT04510597
Recruiting
Phase 1

Imaging of Solid Tumors Using 18F-TRX

Metastatic Malignant Solid NeoplasmStage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8+7 more
Rahul Aggarwal56 enrolled1 locationNCT06942104
Recruiting
Early Phase 1

[18F] PSMA-1007 PET/CT in Metastatic Clear Cell Renal Cell Carcinoma

Metastatic Clear Cell Renal Cell Carcinoma
Western University30 enrolled1 locationNCT06428708
Recruiting
Phase 1

CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

Metastatic Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8+5 more
Osel, Inc.28 enrolled1 locationNCT06399419