Glioma, Malignant Clinical Trials

19 recruiting

Glioma, Malignant Trials at a Glance

19 actively recruiting trials for glioma, malignant are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in New York, Philadelphia, and Boca Raton. Lead sponsors running glioma, malignant studies include Northwell Health, Children's Hospital of Philadelphia, and Beijing Neurosurgical Institute.

Browse glioma, malignant trials by phase

Treatments under study

About Glioma, Malignant Clinical Trials

Looking for clinical trials for Glioma, Malignant? There are currently 19 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Glioma, Malignant trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Glioma, Malignant clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Early Phase 1

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

GliomaGlioma, MalignantLow-grade Glioma+2 more
Children's Hospital of Philadelphia30 enrolled1 locationNCT05555550
Recruiting
Early Phase 1

Window of Opportunity Study of DSP-0390 in Gliomas

Glioma, MalignantIDH Mutation
Washington University School of Medicine20 enrolled1 locationNCT06636162
Recruiting
Phase 1

CUE-102 in Recurrent Glioblastoma

GlioblastomaGlioma, MalignantRecurrent Glioblastoma
David Reardon, MD18 enrolled2 locationsNCT06917885
Recruiting
Not Applicable

Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma

Glioma, Malignant
Institut du Cancer de Montpellier - Val d'Aurelle187 enrolled8 locationsNCT06468176
Recruiting
Early Phase 1

18F-Fluciclovine PET-MRI in High-grade Glioma

GliomaGlioma, MalignantDiffuse Glioma+2 more
Children's Hospital of Philadelphia30 enrolled1 locationNCT05553041
Recruiting
Phase 1

Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma

Glioma, MalignantNew Diagnosis Tumor
Northwestern University20 enrolled1 locationNCT06169280
Recruiting
Phase 1

Imaging of Solid Tumors Using 18F-TRX

Metastatic Malignant Solid NeoplasmStage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8+7 more
Rahul Aggarwal56 enrolled1 locationNCT06942104
Recruiting
Not Applicable

PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial

GliomaGlioma, MalignantRecurrent Glioma
Baptist Health South Florida28 enrolled2 locationsNCT06397560
Recruiting
Phase 1

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

Glioma, Malignant
NanoPharmaceuticals LLC34 enrolled1 locationNCT05226494
Recruiting
Not Applicable

Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases

Glioma, MalignantMetastases to Brain
Sklifosovsky Institute of Emergency Care52 enrolled1 locationNCT05474573
Recruiting
Phase 1

Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

Glioma, Malignant
Darell Bigner90 enrolled1 locationNCT04547777
Recruiting
Early Phase 1

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

GlioblastomaGliomaGlioma, Malignant+1 more
Nader Sanai12 enrolled1 locationNCT05773326
Recruiting
Phase 2

FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma

Glioma, Malignant
Singapore General Hospital22 enrolled2 locationsNCT06172595
Recruiting
Phase 1

Clinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant Glioma

Glioblastoma MultiformeGlioma, Malignant
Beijing Neurosurgical Institute30 enrolled1 locationNCT06585527
Recruiting
Phase 3

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Brain CancerGlioblastomaGBM+4 more
Northwell Health432 enrolled1 locationNCT05271240
Recruiting
Not Applicable

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

Brain CancerGlioblastomaGBM+5 more
Northwell Health10 enrolled1 locationNCT05979064
Recruiting
Not Applicable

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Brain CancerGlioblastomaGBM+4 more
Northwell Health32 enrolled1 locationNCT05954858
Recruiting
Not Applicable

Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life

GliomaGlioma, Malignant
University of Milan400 enrolled1 locationNCT06381726
Recruiting

Monitoring of Patients With Diffuse Gliomas Using Circulating miRNAs

Glioma, Malignant
University Hospital, Caen60 enrolled1 locationNCT06203496