Phase 2 Metastatic Prostate Cancer Clinical Trials
23 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 23 trials
Recruiting
Phase 2
A Study of Tarlatamab for People With Prostate Cancer
Metastatic Prostate Cancer
Memorial Sloan Kettering Cancer Center32 enrolled10 locationsNCT07111507
Recruiting
Phase 1Phase 2
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
Metastatic Prostate Cancer
AstraZeneca177 enrolled51 locationsNCT07181161
Recruiting
Phase 2Phase 3
Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer
Prostate CancerMetastatic Prostate CancerOligometastasis+3 more
VA Office of Research and Development464 enrolled20 locationsNCT04787744
Recruiting
Phase 2
Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression
Castration Resistant Metastatic Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins150 enrolled6 locationsNCT04363164
Recruiting
Phase 2
Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic Prostate Cancer
Prostate CancerMetastatic Prostate Cancer
H. Lee Moffitt Cancer Center and Research Institute26 enrolled2 locationsNCT05751941
Recruiting
Phase 1Phase 2
Study of AZD0754 in Participants With Metastatic Prostate Cancer
Metastatic Prostate Cancer
AstraZeneca60 enrolled15 locationsNCT06267729
Recruiting
Phase 2
Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer
Metastatic Prostate CancerProstate Cancer (Adenocarcinoma)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins58 enrolled1 locationNCT06616597
Recruiting
Phase 2
Prostate Cryoablation Combined With Metronomic Cyclophosphamide for Metastatic Prostate Cancer
Metastatic Prostate Cancer
Sun Yat-sen University104 enrolled1 locationNCT06854250
Recruiting
Phase 2
Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer
Metastatic Prostate CancerMetastatic Castration-resistant Prostate Cancer
Case Comprehensive Cancer Center44 enrolled1 locationNCT06738303
Recruiting
Phase 2
Lu-PSMA for Oligometastatic Prostate Cancer Treated With STereotactic Ablative Radiotherapy
Oligometastatic Prostate Cancer
Peter MacCallum Cancer Centre, Australia92 enrolled3 locationsNCT05560659
Recruiting
Phase 2
High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers
Metastatic Prostate Cancer
VA Office of Research and Development51 enrolled17 locationsNCT05011383
Recruiting
Phase 2
The Impact of Metastatic Directed Radiotherapy (MDRT) on Oligoprogressive Castration Resistant Prostate Cancer (CRPC)
RadiotherapyOligoProgressive Metastatic DiseaseProstate Cancer (Adenocarcinoma)+1 more
University Medical Center Groningen35 enrolled2 locationsNCT07038304
Recruiting
Phase 2
Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer
Oligometastatic Prostate Cancer
Catherine Spina23 enrolled1 locationNCT05915442
Recruiting
Phase 2Phase 3
Maximal Tumor Eradication for Oligometastatic Prostate Cancer
Oligometastatic Prostate Cancer
RenJi Hospital120 enrolled1 locationNCT06972511
Recruiting
Phase 2
Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction
Metastatic Prostate Cancer
St Vincent's Hospital, Sydney22 enrolled2 locationsNCT04925648
Recruiting
Phase 1Phase 2
A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab
Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Pancreatic CancerMetastatic Prostate Cancer
ImmunoGenesis71 enrolled1 locationNCT06782555
Recruiting
Phase 2
Management of Oligoprogressive Castration Resistant Prostate Cancer (PCS X)
Metastatic Prostate CancerCastration-resistant Prostate Cancer
Sir Mortimer B. Davis - Jewish General Hospital66 enrolled10 locationsNCT04070209
Recruiting
Phase 2
Talazoparib Plus Enzalutamide After Progression to Abiraterone in Metastatic Prostate Cancer: (TEAM PC)
Metastatic Prostate Cancer
Fundacion Oncosur78 enrolled12 locationsNCT06582628
Recruiting
Phase 2
Duration of Androgen Receptor Pathway Inhibitor and ADT With Metastasis Directed Therapy in Oligometastatic Cancer of the Prostate (DIRECT)
Metastatic Prostate Cancer
University Health Network, Toronto132 enrolled2 locationsNCT05404139
Recruiting
Phase 2
Combination of TURP and Standard Systemic Therapy for MPCa
Metastatic Prostate Cancer
Fudan University200 enrolled1 locationNCT06655259