Phase 1 Metastatic Uveal Melanoma Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1Phase 2
Tebentafusp-tebn With LDT in Metastatic UM
Metastatic Uveal Melanoma
Thomas Jefferson University109 enrolled1 locationNCT06626516
Recruiting
Phase 1Phase 2
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
Colorectal, CancerCutaneous MelanomaOther Solid Tumors+1 more
IDEAYA Biosciences336 enrolled15 locationsNCT03947385
Recruiting
Phase 1Phase 2
Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma
Unresectable MelanomaMetastatic Cutaneous MelanomaMetastatic Uveal Melanoma
Beijing Biotech36 enrolled1 locationNCT07627698
Recruiting
Phase 1
A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma
MelanomaMetastatic MelanomaUveal Melanoma+1 more
Memorial Sloan Kettering Cancer Center30 enrolled2 locationsNCT05607095
Recruiting
Phase 1
Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Lung Non-Small Cell CarcinomaMetastatic Melanoma+7 more
M.D. Anderson Cancer Center75 enrolled1 locationNCT03025256
Recruiting
Phase 1Phase 2
Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma
Metastatic Uveal MelanomaUveal Melanoma, MetastaticUveal Melanoma, Recurrent+2 more
Novelwise Pharmaceutical Corporation36 enrolled3 locationsNCT07136181
Recruiting
Phase 1Phase 2
Adding IL-2 to Tebentafusp to Eradicate Cancer Progression
Uveal MelanomaMetastatic Uveal MelanomaMetastatic Uveal Melanoma in the Liver
St Vincent's Hospital, Sydney8 enrolled2 locationsNCT07063875