Phase 2 Mitochondria Clinical Trials

7 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 17 of 7 trials

Recruiting
Phase 2

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

Insulin ResistanceChronic Kidney DiseasesFatigue+4 more
University of California, Davis80 enrolled2 locationsNCT04984226
Recruiting
Phase 2

Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

Primary Mitochondrial Disease
Abliva AB180 enrolled35 locationsNCT05650229
Recruiting
Phase 2Phase 3

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

Cognitive ImpairmentMitochondrial AlterationSchizophrenia and Related Disorders
Mclean Hospital100 enrolled3 locationsNCT06191965
Recruiting
Phase 2

A Study to Assess TTI-0102 vs Placebo in MELAS Patients

Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)MELAS Syndrome
Thiogenesis Therapeutics, Inc.12 enrolled2 locationsNCT06644534
Recruiting
Phase 2

Doxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) Deficiency

MItochondrial MyopathiesThymidine Kinase 2 (TK2 ) Deficiency
Cristina Domínguez González15 enrolled1 locationNCT06754098
Recruiting
Phase 2

Evaluate the Safety and Therapeutic Effects of a Single Intravenous Infusion (IV) of Autologous CD34+ Cells Enriched With Allogenic Placenta-derived Mitochondria in Patients With a Diagnosis of Pearson Syndrome (PS)

Mitochondrial DiseasesPearson Syndrome
Minovia Therapeutics Ltd.6 enrolled1 locationNCT06017869
Recruiting
Phase 2

Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome

Mitochondrial DiseasesMitochondrial Metabolism DisordersMitochondrial Encephalomyopathy+2 more
Kenneth Myers, MD200 enrolled1 locationNCT04802707