Phase 1 Myeloproliferative Neoplasms Clinical Trials
8 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–8 of 8 trials
Recruiting
Phase 1
A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms
Myelofibrosis (MF)Polycythemia Vera (PV)Myeloproliferative Neoplasms (MPNs)
Prelude Therapeutics100 enrolled1 locationNCT07469891
Recruiting
Phase 1
A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms
Myeloproliferative Neoplasms
Incyte Corporation290 enrolled13 locationsNCT06034002
Recruiting
Phase 1
Study of INCA036978 in Participants With Myeloproliferative Neoplasms
Myeloproliferative Neoplasms
Incyte Corporation218 enrolled47 locationsNCT07441694
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms
Myeloproliferative Neoplasms
Incyte Corporation186 enrolled31 locationsNCT06313593
Recruiting
Phase 1
A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms
Myeloproliferative Neoplasms
Incyte Corporation120 enrolled26 locationsNCT07008118
Recruiting
Phase 1
A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms
Myeloproliferative Neoplasms
Incyte Corporation225 enrolled29 locationsNCT05936359
Not Yet Recruiting
Phase 1
A Double-Blind, Placebo-Controlled, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZE74-0282 in Healthy Volunteers.
Myeloproliferative Neoplasms (MPN)
Eilean Therapeutics AU Pty Ltd (A subsidiary of Eilean Therapeutics LLC)40 enrolled1 locationACTRN12626000214336
Recruiting
Phase 1
Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation
Myeloproliferative Neoplasms
University of Chicago18 enrolled1 locationNCT06291987