Phase 3 Myocardial Infarct Clinical Trials

23 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 23 trials

Recruiting
Phase 3

Prehospital Pulse-dose Glucocorticoid in Patients With ST-segment Elevation Myocardial Infarction 2 - The PULSE-MI 2 Trial

STEMI - ST Elevation Myocardial Infarction
Thomas Engstrom5,204 enrolled4 locationsNCT07478003
Recruiting
Phase 3

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Cardiovascular RiskAcute Myocardial Infarction (AMI)
Novo Nordisk A/S10,000 enrolled970 locationsNCT06118281
Recruiting
Phase 3

Effects of Ziltivekimab on Coronary Atherosclerotic Burden in Patients With Acute Myocardial Infarction

Coronary Artery DiseaseAcute Myocardial Infarction (AMI)Coronary Atherosclerosis of Native Coronary Artery
ECRI bv332 enrolled1 locationNCT07276282
Recruiting
Phase 3

Aspirin Continuation or Interruption in Patients at Moderate Risk for Cardiovascular Events Undergoing Colonoscopy and/or Polypectomy

Myocardial Infarction (MI)Cardiovascular EventsPost Polypectomy Bleeding in Antiplatelet Patients
Chinese University of Hong Kong2,514 enrolled1 locationNCT07052799
Recruiting
Phase 3

A Research Study to Look at the Effect of Ziltivekimab on Plaque in the Blood Vessels of the Heart, Compared to Placebo, in People With a Heart Attack

Myocardial Infarction
Novo Nordisk A/S332 enrolled20 locationsNCT07301034
Recruiting
Phase 3

Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone

Myocardial InfarctionNSTEMI - Non-ST Segment Elevation MISTEMI (ST Elevation MI)
Montreal Heart Institute2,570 enrolled1 locationNCT07257198
Recruiting
Phase 3

Dapagliflozin in STEMI

Myocardial InfarctionST Elevation Myocardial Infarction
Ottawa Heart Institute Research Corporation256 enrolled1 locationNCT06174753
Recruiting
Phase 3

Assessment of an Early De-Escalation to a Low-potency Single Antiplatelet Therapy Guided by Genetics Versus a Systematic High-Potency Single Antiplatelet Therapy to Neutralize Bleeding Complications in Patients With High Bleeding Risk Beyond One Month After an Acute Coronary Syndrome

Myocardial Infarction
Assistance Publique - Hôpitaux de Paris2,468 enrolled1 locationNCT05577988
Recruiting
Phase 3

Efficacy of Montelukast on STEMl Patients

Myocardial Infarction (MI)
Shanghai Zhongshan Hospital512 enrolled12 locationsNCT07320625
Not Yet Recruiting
Phase 3Phase 4

Prevention of Reperfusion Injury in Myocardial Infarction II - PRIME II

Myocardial Infarction
Te Whatu Ora75 enrolled1 locationACTRN12626000027314
Recruiting
Phase 3

Epicardial Cardiac Fat-CT (EPIC-CT)

Epicardial fatSTEMI - ST Elevation Myocardial Infarction
Instituto Mexicano del Seguro Social136 enrolled1 locationNCT07297589
Recruiting
Phase 3

Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial)

Acute Myocardial Infarction With ST Elevation
Instituto Mexicano del Seguro Social44 enrolled1 locationNCT07295223
Recruiting
Phase 3

Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis

Stroke, IschemicStrokeAtherosclerosis+5 more
Assistance Publique - Hôpitaux de Paris2,800 enrolled1 locationNCT05476991
Recruiting
Phase 2Phase 3

Pleiotropic Effects of Dapagliflozin in Patients With Acute Coronary Syndromes

Ventricular DysfunctionDiabetesAcute Coronary Syndrome+1 more
University of Sao Paulo80 enrolled1 locationNCT06286878
Recruiting
Phase 3

The Investigator Administers Intracoronary Adrenaline Via the Catheter in STEMI Patients During Primary PCI, After Flow Restoration and Before Stenting, and Studies Its Effect in Prevention of No Reflow

ST-segment elevation myocardial infarction (STEMI)No-Reflow Phenomenon
Ain Shams University1,000 enrolled1 locationNCT06847568
Recruiting
Phase 3

Apixaban Prophylaxis for Prevention of Left Ventricular Thrombus Following Anterior Myocardial Infarction

left ventricular thrombusAcute Myocardial Infarction of Anterior WallProphylaxis
National Institute of Cardiovascular Diseases, Pakistan472 enrolled1 locationNCT06742567
Recruiting
Phase 3

Therapeutic Use of Angiopoietin-Primed Autologous Peripheral Blood Stem Cell in Myocardial Infarction

Acute Myocardial Infarction
Seoul National Hospital30 enrolled1 locationNCT06364150
Recruiting
Phase 3

Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET)

PrediabetesAcute Myocardial InfarctionST Elevation Myocardial Infarction+1 more
Karolinska Institutet5,160 enrolled1 locationNCT05182970
Active
Phase 3

Australian Study for the Prevention through Immunisation of Cardiovascular Events

StrokeCardiovascular DiseaseMyocardial Infarction
University of Newcastle4,500 enrolled6 locationsACTRN12615000536561
Withdrawn
Phase 3

Does flow measurement guided stenting of non-culprit lesions as compared with visual assessment guided stenting in patients presenting with a heart attack improve outcomes.

and non-ST elevation myocardial infarction (non-STEMI)
Professor Harvey White850 enrolled1 locationACTRN12615000321549