Phase 2 Narcolepsy Clinical Trials

11 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 111 of 11 trials

Recruiting
Phase 2

A Study of TAK-360 in Adults With Narcolepsy Type 1 (Narcolepsy With Cataplexy)

Narcolepsy Type 1
Takeda92 enrolled1 locationNCT07633301
Recruiting
Phase 2Phase 3

A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence

Narcolepsy Type 1Narcolepsy Type 2
Centessa Pharmaceuticals (UK) Limited222 enrolled2 locationsNCT07598708
Recruiting
Phase 2

A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)

Narcolepsy Type 2
Takeda88 enrolled52 locationsNCT06952699
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy

Narcolepsy
Eisai Inc.64 enrolled57 locationsNCT07493265
Recruiting
Phase 2

A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

Idiopathic HypersomniaNarcolepsy Type 1Narcolepsy Type 2
Centessa Pharmaceuticals (UK) Limited248 enrolled37 locationsNCT06752668
Recruiting
Phase 2

A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

Idiopathic HypersomniaNarcolepsy Type 1Narcolepsy Type 2
Centessa Pharmaceuticals (UK) Limited90 enrolled24 locationsNCT07096674
Recruiting
Phase 2Phase 3

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

Narcolepsy Type 1
Takeda500 enrolled52 locationsNCT05816382
Recruiting
Phase 2Phase 3

A Long-Term Study of ALKS 2680 in Subjects With Narcolepsy and Idiopathic Hypersomnia

Idiopathic HypersomniaNarcolepsy Type 1Narcolepsy Type 2
Alkermes, Inc.256 enrolled46 locationsNCT06767683
Recruiting
Phase 2

Extended-release Sodium Oxybate in Children

Narcolepsy Type 1 (NT 1)
Stanford University36 enrolled1 locationNCT06809803
Not Yet Recruiting
Phase 2

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of BRP-180 in Patients with Narcolepsy

Narcolepsy
Bioron Pharma84 enrolled1 locationACTRN12625000879460
Not Yet Recruiting
Phase 2

A Phase 2 Study of BRP-180 in Patients with Narcolepsy

Narcolepsy
Bioron Pharma75 enrolled1 locationACTRN12625000479404