Phase 1 Neuralgia Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1
Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells Exosomes for Trigeminal Neuralgia
Peripheral NeuropathyTrigeminal Neuralgia
The Foundation for Orthopaedics and Regenerative Medicine20 enrolled1 locationNCT05152368
Recruiting
Phase 1
Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion
Trigeminal Neuralgia
Université de Sherbrooke6 enrolled1 locationNCT05451251
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Properties of iN1011-N17 after Oral Administration in Healthy Volunteers and Post-Herpetic Neuralgia (PHN) Patients
Post Hepatic Neuralgia
iN Therapeutics Co., Ltd.32 enrolled1 locationACTRN12622001300763
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of 2-(diethylamino-N-(2,6-dimethylphenyl)acetamide 5% w/w trandermal patch against the innovator 32-(diethylamino-N-(2,6-dimethylphenyl)acetamide 5% w/w trandermal patch conducted under fasting conditions in healthy male and female volunteers.
2-(diethylamino-N-(2,6-dimethylphenyl)acetamide is used as a local anaesthetic. It is indicated for symptomatic relief of nerve pain associated with medically diagnosed post-herpetic neuralgia (post-shingles pain).
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12622000141741
Completed
Phase 1
A Phase I, Open-Label, Twice Daily Dose, Pharmacokinetic Study of EMA401 Sodium Salt Administered Orally in Healthy Elderly Subjects
Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd8 enrolled1 locationACTRN12610000961044
Completed
Phase 1
A Phase I, Randomised, Open-Label, Three-way Crossover Comparative Pharmacokinetic Study of EMA401 Sodium Salt When Administered Orally in Fed (high fat meal or orange juice only) and Fasted Healthy Adult Males.
Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd15 enrolled1 locationACTRN12610000798066
Completed
Phase 1
A Phase I Multiple Ascending Dose Study of EMA401 Sodium Salt Administered Orally in Healthy Elderly Subjects
Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd32 enrolled1 locationACTRN12610000620022
Completed
Phase 1
A phase I, randomised, double-blind, placebo controlled, dose ranging study to evaluate the safety, tolerability and pharmacokinetics of EMA401 following multiple oral dosing in healthy male subjects.
Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd36 enrolled1 locationACTRN12609000489291
Completed
Phase 1
A Phase I, Randomized, Double-Blind, Placebo-Controlled Dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of EMA401 Following Single Ascending Oral Dosing of EMA401.Na in Healthy Volunteers Administered Orally in the Fasted and Fed State.
Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd.36 enrolled1 locationACTRN12608000335392