Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion
Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion: a Pilot Study
Université de Sherbrooke
6 participants
Oct 15, 2024
INTERVENTIONAL
Conditions
Summary
The aim of this study is to assess the feasibility of deep brain stimulation for refractory trigeminal neuralgia due to a pontine lesion, as is usually seen in the context of multiple sclerosis. These patients usually have severe intractable facial pain and current medical and surgical options generally fail to achieve long lasting pain relief. Hoping to improve pain control in this population, the investigators of this trial propose a novel technique consisting of implanting a deep brain stimulation lead within the pontine lesion to modulate the generation of pain signals.
Eligibility
Inclusion Criteria3
- Adults of at least 18 years old
- Refractory trigeminal neuralgia : failure of at least 3 drugs and at least two lesioning surgical interventions (radiosurgery, percutaneous rhizotomy, or open rhizotomy).
- Pontine lesion proved by MRI in contact with trigeminal nerve tract
Exclusion Criteria2
- Absolute contraindication to MRI
- Medical contraindication to the procedure
Interventions
Implantation of deep brain stimulation lead within the pontine lesion
Locations(1)
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NCT05451251