Phase 2 Neuroendocrine Neoplasm Clinical Trials

13 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 113 of 13 trials

Recruiting
Phase 2

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

Lung Neuroendocrine NeoplasmAdvanced Lung Neuroendocrine TumorFunctioning Lung Neuroendocrine Tumor+9 more
National Cancer Institute (NCI)70 enrolled29 locationsNCT04665739
Recruiting
Phase 2

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

Neuroendocrine TumorsParagangliomaPheochromocytoma+1 more
National Cancer Institute (NCI)130 enrolled1 locationNCT03206060
Recruiting
Phase 2

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

Neuroendocrine NeoplasmsSmall Cell Lung CarcinomaExtra-pulmonary Neuroendocrine Carcinoma
Boehringer Ingelheim204 enrolled59 locationsNCT05882058
Recruiting
Phase 1Phase 2

Lu-177-DOTATATE (Lutathera) in Combination With Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)

Neuroendocrine TumorsNeuroendocrine NeoplasmsGastroenteropancreatico Tumors
National Cancer Institute (NCI)56 enrolled1 locationNCT04086485
Recruiting
Phase 2

Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas

Malignant Solid NeoplasmLung Neuroendocrine NeoplasmDigestive System Neuroendocrine Neoplasm+1 more
Roswell Park Cancer Institute60 enrolled1 locationNCT06202066
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

Neuroendocrine NeoplasmNeuroendocrine TumorsSST2-positive Neuroendocrine Neoplasms
Crinetics Pharmaceuticals Inc.150 enrolled21 locationsNCT07129252
Recruiting
Phase 2

Study to Assess the Safety and Effectiveness of Novel Radiopharmaceutical Terbium-161 DOTATATE in Metastatic Neuroendocrine Tumors

Neuroendocrine TumorsNeuroendocrine Neoplasms (Tumours)Metastatic Neuroendocrine Tumors
Tata Memorial Hospital20 enrolled2 locationsNCT07404176
Recruiting
Phase 2

Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)

High Grade Neuroendocrine Neoplasms
Washington University School of Medicine32 enrolled2 locationsNCT06926634
Recruiting
Phase 2

Sintilimab Combined With IBI310 and Surufatinib for the Treatment of G3-NET and NEC (NESSIE)

Neuroendocrine Neoplasm
Peking University30 enrolled2 locationsNCT05165407
Recruiting
Phase 2Phase 3

Absorbed Tumor Dose in Peptide Receptor Radionuclide Therapy with Long-acting Somatostatin Analogues - ATSA Trial

Neuroendocrine NeoplasmNeuroendocrine TumorsNeuroendocrine Tumor Grade 1+1 more
The Netherlands Cancer Institute39 enrolled1 locationNCT06855095
Recruiting
Phase 2

A Study of PM8002 in Combination With Chemotherapy in Patients With NEN

Neuroendocrine Neoplasm
Biotheus Inc.60 enrolled13 locationsNCT05879055
Recruiting
Phase 2

Dosimetry Based PRRT Versus Standard Dose PRRT With Lu-177-DOTATOC in NEN Patients

Neuroendocrine Neoplasm
Tine Gregersen, MD100 enrolled1 locationNCT04917484
Recruiting
Phase 2

A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GEP-NENS Progressive After Everolimus, Sunitinib or PRRT (CABOTEM)

Lung Neuroendocrine NeoplasmGEP Neuroendocrine Tumor
National Cancer Institute, Naples35 enrolled1 locationNCT04893785