Neurofibroma Clinical Trials

3 recruiting

About Neurofibroma Clinical Trials

Looking for clinical trials for Neurofibroma? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Neurofibroma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Neurofibroma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 35 trials

Recruiting
Not Applicable

A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)

Neurofibromatosis Type 1
National Cancer Institute (NCI)70 enrolled2 locationsNCT06507748
Recruiting

DoD Award NF230020 Identification of Metabolic Markers and Statistical Prediction of MPNST for Rapid Diagnosis and Assessment of Surgical Margins

MPNSTNeurofibromas
M.D. Anderson Cancer Center60 enrolled1 locationNCT07298083
Recruiting

Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study

Neurofibromatosis Type 1Neurofibroma
National Cancer Institute (NCI)110 enrolled1 locationNCT06880991
Recruiting

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

Neurofibromatosis 1Plexiform Neurofibromas
National Cancer Institute (NCI)476 enrolled6 locationsNCT02544022
Recruiting

Natural History Study of Patients With Neurofibromatosis Type 2

Neurofibromatosis
National Institute of Neurological Disorders and Stroke (NINDS)269 enrolled1 locationNCT00598351
Recruiting
Phase 2

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Leukemia+21 more
Masonic Cancer Center, University of Minnesota70 enrolled1 locationNCT05735717
Recruiting
Phase 1Phase 2

Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

Neurofibromatosis 1
National Cancer Institute (NCI)55 enrolled1 locationNCT04750928
Recruiting
Phase 3

Evaluation of TQ-B3234 Capsules in Patients With Symptomatic, Non-Surgical Type 1 Neurofibromatosis-Associated Plexiform Neurofibromas

Plexiform Neurofibroma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.177 enrolled29 locationsNCT07407803
Recruiting

Real-World Treatment Study of Koselugo (Selumetinib)

Neurofibromatosis 1Neurofibroma, Plexiform
AstraZeneca200 enrolled12 locationsNCT06360406
Recruiting

Clinical and Demographic Characteristics of Adult p Atients With NEurofibromatosis in RUSsia

Neurofibromatosis
AstraZeneca200 enrolled13 locationsNCT07088991
Recruiting
Phase 1

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

SarcomaPrecursor Cell Lymphoblastic Leukemia-LymphomaNeurofibroma, Plexiform+1 more
National Cancer Institute (NCI)54 enrolled1 locationNCT02390752
Recruiting
Phase 2

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

Neurofibromatosis Type 1
Healx Limited25 enrolled13 locationsNCT06541847
Recruiting
Phase 2

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

Neurofibromatosis 1Plexiform Neurofibroma
University of Alabama at Birmingham200 enrolled13 locationsNCT06188741
Recruiting
Not Applicable

Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy

Neurofibromatosis 1
Massachusetts General Hospital50 enrolled1 locationNCT07233408
Recruiting
Phase 1

A Study of Avutometinib for People With Solid Tumor Cancers

Solid TumorSolid Tumor, AdultNeuroblastoma+12 more
Memorial Sloan Kettering Cancer Center23 enrolled2 locationsNCT06104488
Recruiting

Prevalence, Clinical Characteristics, Progression, and Management of Neurofibromatosis Type 1 in Egypt (NF1-Egy)

Neurofibromatosis Type 1
AstraZeneca200 enrolled9 locationsNCT07221331
Recruiting
Not Applicable

Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

Neurofibromatosis 1Noonan SyndromeCardiofaciocutaneous Syndrome+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT05361811
Recruiting
Phase 1

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

NeurofibromatosisNF1Cutaneous Neurofibroma+3 more
Johns Hopkins University10 enrolled1 locationNCT07102394
Recruiting

FARD (RaDiCo Cohort) (RaDiCo-FARD)

PemphigusNeurofibromatosis Type 1Ichthyosis+6 more
Institut National de la Santé Et de la Recherche Médicale, France900 enrolled15 locationsNCT05954416
Recruiting

Familial Investigations of Childhood Cancer Predisposition

Hereditary Breast and Ovarian CancerHodgkin LymphomaAdrenocortical Carcinoma+30 more
St. Jude Children's Research Hospital1,500 enrolled1 locationNCT03050268