Phase 2 Neurofibroma Clinical Trials
10 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–10 of 10 trials
Recruiting
Phase 2
A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1
Neurofibromatosis Type 1
Healx Limited25 enrolled14 locationsNCT06541847
Recruiting
Phase 2
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)
Neurofibromatosis type 2MeningiomaEpendymoma+2 more
Scott R. Plotkin, MD, PhD109 enrolled6 locationsNCT04374305
Recruiting
Phase 1Phase 2
Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas
Neurofibromatosis 1
National Cancer Institute (NCI)55 enrolled1 locationNCT04750928
Recruiting
Phase 1Phase 2
A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia
Neurofibromatosis 1Leukemia, Juvenile MyelomonocyticJMML+2 more
Therapeutic Advances in Childhood Leukemia Consortium58 enrolled19 locationsNCT05849662
Recruiting
Phase 1Phase 2
Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).
NF1Cutaneous NeurofibromaMonotherapy
Johns Hopkins University24 enrolled1 locationNCT06159166
Recruiting
Phase 2
MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Leukemia+21 more
Masonic Cancer Center, University of Minnesota70 enrolled1 locationNCT05735717
Recruiting
Phase 2
Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1
Neurofibromatosis 1Plexiform Neurofibroma
University of Alabama at Birmingham200 enrolled13 locationsNCT06188741
Recruiting
Phase 2
Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II
Neurofibromatosis 1
Donald Basel30 enrolled1 locationNCT02728388
Recruiting
Phase 2
HL-085 in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas
Neurofibromatosis 1Plexiform Neurofibromas
Shanghai Kechow Pharma, Inc.70 enrolled1 locationNCT05331105
Active
Phase 2
TiNT: Trametinib in Neurofibromatosis type 1 associated tumours
Optic pathway gliomaPlexiform neurofibromatosis
Australian and New Zealand Children's Haematology/Oncology Group120 enrolled11 locationsACTRN12620001229965