Phase 1 Neurofibromatosis 1 Clinical Trials

2 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–2 of 2 trials

Recruiting

Phase 1Phase 2

Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

Neurofibromatosis 1

National Cancer Institute (NCI)55 enrolled1 locationNCT04750928

Recruiting

Phase 1Phase 2

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Neurofibromatosis 1Leukemia, Juvenile MyelomonocyticJMML+2 more

Therapeutic Advances in Childhood Leukemia Consortium58 enrolled19 locationsNCT05849662