Phase 1 Neurological Clinical Trials

5 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 15 of 5 trials

Recruiting
Phase 1

ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant Gliomas

Neurological Cancer
Massachusetts General Hospital18 enrolled3 locationsNCT03922555
Recruiting
Phase 1

GT719 Injection for Recurrent/Refractory Antibody-mediated Neurological Immune Diseases

Neurological Autoimmune Diseases
Grit Biotechnology30 enrolled1 locationNCT07021209
Completed
Phase 1

A Phase 1, 2-Part, Open-Label, Pilot Trial to Assess the Relative Bioavailability of 3 Formulations of Cannabidiol (CBD) under FASTED (Part A) and FED (Part B) conditions in Healthy Adult Male Subjects.

Neurological
Sapient Therapeutics (Australia) PTY Ltd15 enrolled1 locationACTRN12623000730606
Completed
Phase 1

Comparative assessment of the absorption of a generic formulation of 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine oral suspension against the innovator 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine oral tablet conducted under fasting conditions in healthy male and female volunteers.

3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine is indicated for treatment-resistant schizophrenic patients and in schizophrenia patients who have severe, untreatable neurological adverse reactions to other antipsychotic agents, including atypical antipsychotics.
Zenith Technology Corporation Limited28 enrolled1 locationACTRN12621001490864
Completed
Phase 1

Safety and tolerability of psilocybin-assisted physiotherapy in healthy volunteers

Functional neurological disorder
Austin Health12 enrolled2 locationsACTRN12621000560897