Phase 1 Neuropathic Pain Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1Phase 2

Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study

Diabetic NeuropathiesDiabetic Peripheral Neuropathic Pain (DPN)
Florida A&M University20 enrolled1 locationNCT07298408
Recruiting
Phase 1Phase 2

Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)

Chronic Neuropathic Pain
Sangamo Therapeutics27 enrolled11 locationsNCT06980948
Recruiting
Phase 1

Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury

Spinal StenosisDegenerative Disc DiseaseSpinal Cord Injuries+2 more
EicOsis Human Health Inc.36 enrolled1 locationNCT06438471
Recruiting
Phase 1Phase 2

Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI

Neuropathic PainSCI - Spinal Cord Injury
University of Miami20 enrolled1 locationNCT05630235
Completed
Phase 1

A Phase 1, Randomized, Double-Blind, Placebo-Controlled Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of STC-004

Chronic, peripheral neuropathic pain
SiteOne Therapeutics76 enrolled1 locationACTRN12624000642583
Completed
Phase 1

Study of ZYN001 (transdermal patch) in Healthy Volunteers

Peripheral neuropathic painFibromyalgia
Zynerba Pharmaceuticals Pty. Ltd20 enrolled1 locationACTRN12617001028392
Completed
Phase 1

A Phase 1, Randomised, Open-Label, Three-way Crossover Comparative Pharmacokinetic Study of Capsule and Tablet Dosage Forms of EMA401 Sodium Salt When Administered Orally in Healthy Adult Males

Neuropathic Pain
Spinifex Pharmaceuticals Pty Ltd15 enrolled1 locationACTRN12615000074594
Completed
Phase 1

A Phase 1, Adaptive, Single and Multiple Ascending Dose Study of EMA401 Sodium Salt Administered Orally in Healthy, Adult Males to Determine the Maximum Tolerated Dose and Pharmacokinetic Profiles

Neuropathic Pain
Spinifex Pharmaceuticals Pty Ltd84 enrolled1 locationACTRN12614000802606