Phase 2 Non-small Cell Lung Cancer Clinical Trials
85 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 85 trials
Recruiting
Phase 2Phase 3
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
Non-small Cell Lung Cancer
BioNTech SE1,260 enrolled184 locationsNCT06712316
Recruiting
Phase 1Phase 2
A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
MelanomaNon-small Cell Lung CancerSquamous Cell Carcinoma (Skin)+2 more
AstraZeneca60 enrolled11 locationsNCT07115043
Recruiting
Phase 2
Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment
Non-small Cell Lung Cancer
BioNTech SE60 enrolled30 locationsNCT06841055
Recruiting
Phase 2
Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer
Non-small Cell Lung Cancer
AstraZeneca630 enrolled99 locationsNCT05061550
Recruiting
Phase 2
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer
Genentech, Inc.99 enrolled38 locationsNCT04302025
Recruiting
Phase 2
Stereotactic Radiotherapy (SBRT) of Lung Metastasis
Non-small Cell Lung CancerMetastasis From Other Cancers
University Health Network, Toronto200 enrolled1 locationNCT01803542
Recruiting
Phase 1Phase 2
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
Endometrial CancerPrimary Peritoneal CarcinomaNon-small Cell Lung Cancer+6 more
Genmab764 enrolled67 locationsNCT05579366
Recruiting
Phase 1Phase 2
FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC
Ovarian CancerNon-small Cell Lung Cancer
Tubulis GmbH250 enrolled15 locationsNCT06303505
Recruiting
Phase 2
Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC
Non-small Cell Lung Cancer
H. Lee Moffitt Cancer Center and Research Institute318 enrolled4 locationsNCT06745882
Recruiting
Phase 2
Volrustomig Priming Regimens Exploratory Phase II Platform Study
Non-small Cell Lung Cancer
AstraZeneca180 enrolled77 locationsNCT06448754
Recruiting
Phase 2
A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC90 enrolled41 locationsNCT06731907
Recruiting
Phase 2
Adjuvant ctDNA-Adapted Personalized Treatment in Early Stage NSCLC (ADAPT-E)
Non-small Cell Lung CancerNon-small Cell Lung Cancer Stage INon-small Cell Lung Cancer Stage II
Stanford University80 enrolled1 locationNCT04585477
Recruiting
Phase 2
Neoadjuvant Lazertinib With or Without Chemotherapy for Patients With EGFR-mutated Resectable Non-small Cell Lung Cancer
Non-small Cell Lung Cancer
Yonsei University160 enrolled1 locationNCT06268210
Recruiting
Phase 1Phase 2
Synapse 3D With Intravascular Indocyanine Green
Non-small Cell Lung CancerPrimary Neoplasm
St. Joseph's Healthcare Hamilton32 enrolled1 locationNCT03953144
Recruiting
Phase 2
A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors
Non-small Cell Lung CancerSolid TumorNasopharyngeal Carcinoma
Sichuan Baili Pharmaceutical Co., Ltd.570 enrolled1 locationNCT06475300
Recruiting
Phase 2
Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance
Non-small Cell Lung Cancer
Abramson Cancer Center at Penn Medicine59 enrolled1 locationNCT04332367
Recruiting
Phase 1Phase 2
Study of ZG005 Combined With Gecacitinib in Patients With Advanced Non-Small Cell Lung Cancer
Non-small Cell Lung Cancer
Suzhou Zelgen Biopharmaceuticals Co.,Ltd50 enrolled1 locationNCT06903377
Recruiting
Phase 2
Low-Dose Radiation + SBRT + Tislelizumab Plus Platinum-based Chemotherapy in Stage ⅡA-ⅢB Non-small Cell Lung Cancer
Lung CancerNon-small Cell Lung Cancer
Sichuan University30 enrolled1 locationNCT06877299
Recruiting
Phase 2
A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)
Non-small Cell Lung Cancer
Dizal Pharmaceuticals90 enrolled4 locationsNCT06295432
Recruiting
Phase 2
A Study of SHR-A2102 in Combination With Other Anti-tumor Therapies for Resectable Non-small Cell Lung Cancer
Non-small Cell Lung Cancer
Shanghai Hengrui Pharmaceutical Co., Ltd.300 enrolled1 locationNCT07229729