Phase 1 Normal Clinical Trials
13 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–13 of 13 trials
Recruiting
Phase 1Phase 2
A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
Noise-induced hearing lossHearing LossHearing Disorders+22 more
University of Colorado, Denver344 enrolled1 locationNCT07304024
Recruiting
Phase 1
AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
Advanced MelanomaAdvanced Melanoma and Normal or Impaired
Yale University50 enrolled1 locationNCT07027488
Recruiting
Phase 1
FAPI-74 PET/CT in Adults With Fibrosis
Fibrosis (Morphologic Abnormality)
Abramson Cancer Center at Penn Medicine45 enrolled1 locationNCT06413355
Recruiting
Phase 1Phase 2
Clinical Application of Al18F-NOTA-FAPI-04 PET/CT or PET/MRI Imaging in Malignant Tumor,Cardiovascular or Immune Disease
Malignant TumorHyperthyroidism, AutoimmuneCardiovascular Abnormalities
Peking Union Medical College Hospital600 enrolled1 locationNCT07400224
Recruiting
Phase 1
Evaluation of Safety, Efficacy, and Pharmacokinetics of BT-114143 Injection in Patients With Abnormal Uterine Bleeding
Abnormal Uterine Bleeding
ScinnoHub Pharmaceutical Co., Ltd.39 enrolled1 locationNCT07169214
Recruiting
Phase 1
Safety, Tolerability and PK of ATTO-3712 in Healthy Volunteers and Patients With Atopic Dermatitis
Atopic eczemaAtopic Dermatitis (AD)Normal Volunteers+1 more
Attovia Therapeutics Inc72 enrolled1 locationNCT07205081
Recruiting
Phase 1
Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy
AnalgesiaAbnormal Uterine BleedingParacervical Block
Icahn School of Medicine at Mount Sinai60 enrolled1 locationNCT06653400
Recruiting
Phase 1Phase 2
Spermatogonial Differentiation Via Testicular Organoid
Gene AbnormalityInfertility, MaleSterility, Male
CellARTs Inc.100 enrolled1 locationNCT06841861
Completed
Phase 1
Effect of ONC201 on Cardiac Repolarization in Healthy Participants - Part 1
CancerSolid TumoursAbnormal cardiac repolarization
Chimerix, Inc.6 enrolled1 locationACTRN12622001021763
Completed
Phase 1
Effect of ONC201 on Cardiac Repolarization in Healthy Participants - Part 2
CancerSolid TumoursAbnormal cardiac repolarization
Chimerix, Inc.30 enrolled1 locationACTRN12622001020774
Completed
Phase 1
Study to Assess the Minimum Effective Concentration of NVK031 on Pupillary Constriction and Distance Vision in Healthy Volunteers
Normal eye function
Nevakar, Inc.44 enrolled2 locationsACTRN12621000351819
Completed
Phase 1
A Phase 1 single ascending study in healthy Caucasian and Japanese Adult subjects to evaluate the Safety, Tolerability, and Pharmacokinetics of CSL346.
HyperglycemiaDyslipidemiaAbnormal lipid accumulation
CSL Limited116 enrolled1 locationACTRN12617001554358
Recruiting
Phase 1
A study on the satiety effect of Caralluma fimbriata extract for people with Prader - Willi syndrome (PWS).”
Prader-Willi syndrome (PWS) PWS is caused by three types of abnormality in chromosome 15 at a prevalence rate of 1:11,000 to 1:22,000. The defining feature of PWS is food-seeking behaviour due to constant hunger. Hyperphagia and obesity are one of the main burdens in PWS and obesity is linked to increased morbidity and mortality.
Victoria University16 enrolled1 locationACTRN12611000334909