Ocular Melanoma Clinical Trials

5 recruiting

Ocular Melanoma Trials at a Glance

7 actively recruiting trials for ocular melanoma are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Phase 2 with 3 trials, with the heaviest enrollment activity in Nashville, Tampa, and Denver. Lead sponsors running ocular melanoma studies include Aura Biosciences, Gustav Stalhammar, and H. Lee Moffitt Cancer Center and Research Institute.

Browse ocular melanoma trials by phase

Treatments under study

About Ocular Melanoma Clinical Trials

Looking for clinical trials for Ocular Melanoma? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Ocular Melanoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Ocular Melanoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Phase 2

Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma

Uveal MelanomaOcular Melanoma
H. Lee Moffitt Cancer Center and Research Institute37 enrolled1 locationNCT05524935
Recruiting
Phase 3

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

Uveal MelanomaChoroidal MelanomaIndeterminate Lesions+1 more
Aura Biosciences100 enrolled71 locationsNCT06007690
Recruiting

Choroidal Melanoma Patient-Reported Outcome Study (CM-PRO) in a Subset of AU-011-301 (CoMpass) Subjects

Uveal MelanomaChoroidal MelanomaIndeterminate Lesions+1 more
Aura Biosciences15 enrolled1 locationNCT07421739
Recruiting
Phase 1Phase 2

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

Metastatic MelanomaUnresectable MelanomaOcular Melanoma
Iovance Biotherapeutics, Inc.42 enrolled4 locationsNCT06940739
Recruiting
Phase 1Phase 2

Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma

Metastatic Uveal MelanomaUveal Melanoma, MetastaticUveal Melanoma, Recurrent+2 more
Novelwise Pharmaceutical Corporation36 enrolled3 locationsNCT07136181
Recruiting
Not Applicable

Resistance Exercise in Patients With Ocular Melanoma

Ocular Melanoma
University of Valencia40 enrolled1 locationNCT06970236
Recruiting
Phase 3

Adjuvant Melatonin for Uveal Melanoma

Uveal MelanomaEye Cancer, Intraocular MelanomaUveal Melanoma, Posterior, Medium/Large Size
Gustav Stalhammar100 enrolled1 locationNCT05502900