RecruitingNot ApplicableNCT06970236

Resistance Exercise in Patients With Ocular Melanoma

Impact of an In-hospital Exercise Program on the Health of Patients With Ocular Melanoma Undergoing Plaque Brachytherapy: A Randomized Controlled Trial

Sponsor

University of Valencia

Enrollment

40 participants

Start Date

Feb 1, 2025

Study Type

INTERVENTIONAL

Conditions

Ocular Melanoma

Summary

Choroidal melanoma (CM) is one of the most common intraocular cancers worldwide. During treatment with episcleral brachytherapy, patients require a week of hospitalization in isolation. The primary aim of this study will be to investigate the effects of resistance training during hospitalization on health-related blood biomarkers in CM patients. Our secondary aim will be to assess changes in physical function tests, quality of life and anxiety and depression. Candidates for this study will be patients undergoing CM treatment at the "Hospital Universitari i Politècnic La Fe" of Valencia.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is exploring whether resistance exercise training can improve the quality of life, physical strength, and mental wellbeing of patients with choroidal melanoma (a type of eye cancer) who are being treated with plaque brachytherapy (targeted radiation delivered directly to the eye). **You may be eligible if...** - You have been diagnosed with choroidal melanoma - You are receiving plaque brachytherapy treatment at Hospital Universitari i Politècnic La Fe in Valencia - You are an adult able to participate in resistance training **You may NOT be eligible if...** - Your overall health makes high-intensity exercise unsafe (such as unstable heart conditions) - You have a serious metabolic disorder - You have an orthopedic condition that prevents you from exercising - You have other serious uncontrolled medical conditions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERExercise

Daily session during hospitalization. To carry out the training session, elastic bands (TheraBand CLX Consecutive Loops; TheraBand, Akron, OH) with resistance graded from very low to very high (i.e, yellow, red, green, blue, black, silver and gold) will be used. On each day, each exercise will start with 3 sets of two repetitions as a warm-up and to calculate the appropriate intensity. The intensity will be that at which the patient reports a perceived exertion of 5-6 of 10 at the Borg CR10 scale after two repetitions. For each exercise, one set will be completed until task failure is achieved.If in any of the exercises the patient perceives this intensity only with the weight of his own limb or body weight, the exercise will be performed without elastic bands.