Older Adult Clinical Trials

128 recruitingLast updated: July 25, 2026

There are 128 actively recruiting older adult clinical trials across 24 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4. Top locations include Hong Kong, Hong Kong, San Francisco, California, United States, Taipei, Taiwan. Updated daily from ClinicalTrials.gov.


Older Adult Trials at a Glance

128 actively recruiting trials for older adult are listed on ClinicalTrialsFinder across 6 cities in 24 countries. The largest study group is Not Applicable with 96 trials, with the heaviest enrollment activity in Hong Kong, San Francisco, and Taipei. Lead sponsors running older adult studies include The Hong Kong Polytechnic University, University of California, San Francisco, and Haukeland University Hospital.

Browse older adult trials by phase

Treatments under study

About Older Adult Clinical Trials

Looking for clinical trials for Older Adult? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Older Adult trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Older Adult clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 128 trials

Recruiting
Not Applicable

Virtual Reality-Enhanced Behavioral Activation for Older Adults With Depression

Depression - Major Depressive DisorderOlder Adults (65 Years and Older)Behavioral Activation Treatment+1 more
Stanford University30 enrolled1 locationNCT07188623
Recruiting

Comparison of Preoperative Frailty Assessment Tools

FrailtyFrailty/SarcopeniaFrailty in Older Adults
Universitätsklinikum Hamburg-Eppendorf584 enrolled1 locationNCT06889545
Recruiting
Not Applicable

Tech-based Respite Care for Caregivers and Homebound Older Adults

Cognitive decline in older adultsCaregiver StressSocial Isolation in Older Adults+2 more
Hong Kong University180 enrolled1 locationNCT07160673
Recruiting

The Better, Harder, Faster, Stronger Study

Ovarian CancerEndometrial CancerNeoadjuvant Chemotherapy+2 more
Wake Forest University Health Sciences35 enrolled1 locationNCT07220512
Recruiting
Phase 2

Mindful Walking Neural Correlates of Executive Function in SC Older Adults at Risk of Dementias

Older Adults With Elevated Dementia Risk
University of South Carolina54 enrolled1 locationNCT07638046
Recruiting

Orthopedic Procedures and Postoperative Delirium in Older Adults in the Czech Republic

Hip ArthroplastyOlder AdultsCognitive Impairment+2 more
Tomas Bata Hospital, Czech Republic400 enrolled7 locationsNCT07432009
Recruiting
Not Applicable

Moving Yourself in Space and Time: MYSTIC

Parkinson's Disease (PD)Older Adults (60 - 85 Years Old)Alzheimer's Disease (AD) and Related Disorders
Emory University210 enrolled1 locationNCT07697664
Recruiting
Not Applicable

Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline

Older AdultsPhysical ActivityChronic Pain+1 more
Massachusetts General Hospital400 enrolled1 locationNCT06246929
Recruiting
Not Applicable

A Pilot Randomized Controlled Trial of a Social Network Intervention

Advanced CancerOlder Adults (65 Years and Older)Social Networks
University of Rochester70 enrolled1 locationNCT07393529
Recruiting

Frailty, Dual-Task Performance, and Activities of Daily Living in Older Adults

Older Adults (60 - 85 Years Old)
KTO Karatay University200 enrolled1 locationNCT07415382
Recruiting
Phase 1

Safety and Tolerability Trial of Psilocybin in Healthy Older Adults

Healthy VolunteerOlder Adults (65-85 Years)
University of Colorado, Denver40 enrolled6 locationsNCT07516405
Recruiting
Not Applicable

Beetroot Extract and Quality of Life in Adults Aged 75 and Over

Cardiovascular HealthPhysical Performance Decline in Older AdultsCognitive Function Decline+1 more
Fundacion Miguel Servet120 enrolled1 locationNCT07666685
Recruiting
Not Applicable

Increasing Physical Activity Through Social Support and Stress Resilience

Sedentary BehaviorHealthySubjective Cognitive Decline (SCD)+1 more
Arizona State University86 enrolled1 locationNCT06896825
Recruiting
Not Applicable

Person-Centered Occupational Therapy in Older Adults

Older AdultsTelerehabilitation
Atlas University154 enrolled1 locationNCT07672366
Recruiting

Clinical Relevance of Ultrasound-based Intramuscular Fat Infiltration Assessment in Hospitalized Older Adults (FATUS-OLD)

SarcopeniaPhysical Performance Decline in Older AdultsMuscle Fat Infiltration
Nantes University Hospital115 enrolled1 locationNCT07411547
Recruiting
Phase 2

Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.

immobilityOlder Adults (65 Years and Older)Hospital Associated Disability
Vrije Universiteit Brussel120 enrolled3 locationsNCT07294131
Recruiting
Not Applicable

eCardiacRehab - a Hybrid Patient-Centered eHealth Programme

Comorbidities and Coexisting ConditionsOlder Adults (65 Years and Older)Mental Health+10 more
Haukeland University Hospital1,000 enrolled1 locationNCT07590635
Recruiting
Not Applicable

Interactive Effects of Sodium and Potassium on Vascular Health in Older Adults

Healthy Older Adults
Florida State University30 enrolled1 locationNCT07649005
Recruiting
Not Applicable

Evaluating Health Outcomes of AI-Based Fitness Wearables and App Programs in Older Adults Living Alone With Cognitive Decline

Older AdultsPhysical InactivityPhysical Activity+4 more
The University of Tennessee, Knoxville64 enrolled2 locationsNCT07207993
Recruiting
Not Applicable

Community-Based Social Connection Intervention Program to Improve Cardiovascular and Brain Health

Cognitive DeclineStrokeLoneliness+1 more
Universidad de Especialidades Espiritu Santo500 enrolled1 locationNCT07319663