Phase 2 Oligoprogressive Clinical Trials

6 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 16 of 6 trials

Recruiting
Phase 2

Trial Of Stereotactic Body Radiation Therapy (SBRT) for Oligoprogression on Immune Checkpoint Inhibitors (ICI) in Metastatic Renal Cell Carcinoma

Metastatic Renal Cell CarcinomaRenal Cell CarcinomaOligoprogressive+1 more
Yale University30 enrolled1 locationNCT04974671
Recruiting
Phase 2Phase 3

A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)

OligoProgressive Metastatic Disease
M.D. Anderson Cancer Center400 enrolled1 locationNCT06367972
Recruiting
Phase 2

Stereotactic Body Radiotherapy or Standard of Care for Prostate Oligoprogressive Cancer

OligoProgressive Metastatic DiseaseCastrate Resistance Prostate Cancer
University Health Network, Toronto75 enrolled1 locationNCT06927635
Recruiting
Phase 2

The Impact of Metastatic Directed Radiotherapy (MDRT) on Oligoprogressive Castration Resistant Prostate Cancer (CRPC)

RadiotherapyOligoProgressive Metastatic DiseaseProstate Cancer (Adenocarcinoma)+1 more
University Medical Center Groningen35 enrolled2 locationsNCT07038304
Recruiting
Phase 2

COntinue the SaMe Systemic Therapy After Local Ablative Therapy for Oligo Progression in Metastatic Breast Cancer - the COSMO Study

Breast Cancer InvasiveMetastatic CancerOligoprogressive
The Netherlands Cancer Institute118 enrolled7 locationsNCT05301881
Recruiting
Phase 2

Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic Cancer

Head and Neck CancerMetastatic CancerOligoprogressive
Centre hospitalier de l'Université de Montréal (CHUM)46 enrolled1 locationNCT04989725