Open-angle Glaucoma (OAG) Clinical Trials

9 recruiting

Frequently Asked Questions

Common questions about Open-angle Glaucoma (OAG) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Phase 1

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

Open-angle Glaucoma (OAG)NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)
Life Biosciences Inc.18 enrolled2 locationsNCT07290244
Recruiting

Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg

Ocular Hypertension (OH)Open-angle Glaucoma (OAG)
Glaukos Corporation30 enrolled1 locationNCT07400926
Recruiting
Phase 2

Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

Normal Tension Glaucoma (NTG)Non-proliferative Diabetic Retinopathy (NPDR)Open-angle Glaucoma (OAG)
Qlaris Bio, Inc.14 enrolled1 locationNCT07354477
Recruiting
Not Applicable

iStent Inject Versus Goniotomy With Kahook Dual Blade in Glauocma Treatment

Open-angle Glaucoma (OAG)
Medical University of Bialystok100 enrolled2 locationsNCT07325552
Recruiting
Phase 1

Evaluate Efficacy, Safety, Tolerability and Biodegradation of PA5346 Ocular Implant in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension (OH)Open-angle Glaucoma (OAG)
PolyActiva Pty Ltd12 enrolled3 locationsNCT06964061
Recruiting
Not Applicable

Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

Open-angle Glaucoma (OAG)
Avisi Technologies Inc.165 enrolled12 locationsNCT07220876
Recruiting

DSLT Performance in Treatment-naïve Patients With Newly Diagnosed Open Angle Glaucoma

Open-angle Glaucoma (OAG)
Barnet Dulaney Perkins Eye Centers55 enrolled1 locationNCT06933836
Recruiting
Not Applicable

Efficacy and Safety of Gonioscopy Assisted Transluminal Trabeculotomy in Patients with Primary Open-angle Glaucoma and Cataract.

Open-angle Glaucoma (OAG)
Faculdade de Ciências Médicas de Minas Gerais90 enrolled1 locationNCT06865235
Recruiting

Long-term Safety and Efficacy of a Modified Suprachoroidal Silicone Tube (SST) Shunt

GlaucomaOcular HypertensionOpen-angle Glaucoma (OAG)+3 more
Davinci LTD66 enrolled1 locationNCT06691555