Phase 1 PALB2 Gene Mutation Clinical Trials

3 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–3 of 3 trials

Recruiting

Phase 1

Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors

BRCA MutationBRCA1 MutationBRCA2 Mutation+3 more

Varun Monga, MBBS18 enrolled1 locationNCT06177171

Recruiting

Phase 1

Combination Therapy in Cancers With Mutations in DNA Repair Genes

Metastatic Solid TumorBRCA1 MutationBRCA2 Mutation+2 more

University of California, San Francisco24 enrolled1 locationNCT05694715

Recruiting

Phase 1

SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

Breast Cancer MetastaticHER2-Negative Breast CarcinomaPancreatic Cancer+17 more

General Oncology, Inc.24 enrolled2 locationsNCT04150042