Phase 1 Pancreatic Cancer Clinical Trials

20 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 120 of 20 trials

Recruiting
Phase 1

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

Pancreatic CancerLung CancerColon Cancer+3 more
RasCal Therapeutics, Inc.134 enrolled3 locationsNCT04678648
Recruiting
Phase 1

A Study to Test Different Doses of BI 765049 Alone and in Combination With Ezabenlimab in Asian People With Advanced Cancer (Solid Tumours) Positive for B7-H6

Pancreatic CancerLung CancerGastrointestinal Cancer
Boehringer Ingelheim97 enrolled7 locationsNCT06091930
Recruiting
Phase 1

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

Pancreatic CancerNon-small Cell Lung Cancer (NSCLC)Pancreatic Ductal Adenocarcinoma (PDAC)+7 more
Revolution Medicines, Inc.574 enrolled5 locationsNCT07349537
Recruiting
Phase 1

A Study of PHN-012 in Patients With Advanced Solid Tumors

Pancreatic CancerColon CancerAdvanced Cancer+2 more
Pheon Therapeutics165 enrolled7 locationsNCT07127874
Recruiting
Phase 1

SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

Breast Cancer MetastaticPancreatic CancerHER2-negative Breast Cancer+9 more
General Oncology, Inc.24 enrolled2 locationsNCT04150042
Recruiting
Phase 1Phase 2

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Breast CancerPancreatic CancerOvarian Cancer+2 more
National Cancer Institute (NCI)124 enrolled1 locationNCT02830724
Recruiting
Phase 1

A Pilot Study to Assess the Clinical Utility of PYLARIFY PET-CT for Detecting Metastasis in Pancreatic Cancer, Hepatocellular Carcinoma and Breast Cancer

Breast CancerPancreatic CancerHepatocellular Carcinoma
M.D. Anderson Cancer Center36 enrolled1 locationNCT05394259
Recruiting
Phase 1Phase 2

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

Pancreatic CancerGastric CancerColon Cancer+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT03745326
Recruiting
Phase 1

A Study of BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Lower Expression Gastrointestinal Cancer and Other Solid Tumors

Esophageal CancerPancreatic CancerGastric Cancer
Sichuan Baili Pharmaceutical Co., Ltd.20 enrolled1 locationNCT06500052
Recruiting
Phase 1Phase 2

A Study of GI-108, an Anti-CD73-IgG4 Fc-IL-2v Bispecific Fusion Protein, as Monotherapy in Patients With Advanced or Metastatic Solid Tumors

Pancreatic CancerNon-small Cell Lung Cancer (NSCLC)Advanced Solid Tumor+3 more
GI Innovation, Inc.76 enrolled3 locationsNCT07172802
Recruiting
Phase 1

Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients

Liver CancerPancreatic CancerGastric Cancer+6 more
Arbele Pty Ltd68 enrolled3 locationsNCT05411133
Recruiting
Phase 1

A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors

Breast CancerPancreatic CancerGastric Cancer+6 more
GONGCHU Biotechnology Co., Ltd21 enrolled1 locationNCT06508307
Recruiting
Phase 1Phase 2

64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

Esophageal CancerPancreatic CancerGastric Cancer+1 more
Lantheus Medical Imaging26 enrolled5 locationsNCT06298916
Recruiting
Phase 1

A Study of Hansoh (HS)-10502 in Patients With Advanced Solid Tumors

Breast CancerPancreatic CancerOvarian Cancer+1 more
Jiangsu Hansoh Pharmaceutical Co., Ltd.318 enrolled1 locationNCT05740956
Recruiting
Phase 1

Brodalumab in the Treatment of Immune-Related Adverse Events

Breast CancerLiver CancerEsophageal Cancer+15 more
Brian Henick, MD11 enrolled1 locationNCT06673329
Recruiting
Phase 1Phase 2

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

Breast CancerPancreatic CancerOvarian Cancer+3 more
AtlasMedx, Incorporated122 enrolled4 locationsNCT04503265
Recruiting
Phase 1Phase 2

Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors

Breast CancerPancreatic CancerCancer+7 more
Zhejiang Yangli Pharmaceutical Technology Co., Ltd.188 enrolled1 locationNCT06819215
Recruiting
Phase 1Phase 2

CTS2190 Phase I /II Clinical Study in Patients

Pancreatic CancerSolid TumorsNon-small Cell Lung Cancer
CytosinLab Therapeutics Co., Ltd.224 enrolled2 locationsNCT06224387
Recruiting
Phase 1

IX001 TCR-T In the Treatment of Advanced Pancreatic Cancer and Colorectal Cancer Induced by KRAS Mutations

Pancreatic Cancer
Shanghai Pudong Hospital12 enrolled1 locationNCT06487377
Recruiting
Phase 1

A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

Breast CancerPancreatic CancerOvarian Cancer+1 more
Qurgen Inc.150 enrolled5 locationsNCT05989724