Phase 1 Pediatric Solid Tumor Clinical Trials

6 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–6 of 6 trials

Recruiting

Phase 1

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Advanced Breast CancerAdvanced Solid TumorsMetastatic Pancreatic Cancer+3 more

National Cancer Institute (NCI)116 enrolled2 locationsNCT04222413

Recruiting

Phase 1

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

Soft Tissue SarcomaMelanomaCarcinoma+13 more

St. Jude Children's Research Hospital48 enrolled1 locationNCT04897321

Recruiting

Phase 1

Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

Pediatric Solid TumorPediatric Brain Tumor

Washington University School of Medicine20 enrolled1 locationNCT05521984

Recruiting

Phase 1Phase 2

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

Hepatocellular CarcinomaRefractory Solid TumorPediatric Solid Tumor+3 more

St. Jude Children's Research Hospital64 enrolled2 locationsNCT05468359

Recruiting

Phase 1

Clinical Trial of GAIA-102 for Refractory/Relapse Neuroblastomas and Other Malignant Pediatric Solid Tumors

Pediatric Solid TumorsRefractory/Relapse Neuroblastoma

Kyushu University61 enrolled1 locationNCT05608148

Recruiting

Phase 1

UGT1A1 Genotype-drien Phase I Study of Irinotecan in VIT Regimen for the Treatment of Pediatric R/R Solid Tumors

Pediatric Solid Tumor

Sun Yat-sen University39 enrolled1 locationNCT06760117