Phase 1 Philadelphia Chromosome Positive Clinical Trials

3 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–3 of 3 trials

Recruiting

Phase 1Phase 2

Phase I/II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Acute Lymphoblastic LeukemiaPhiladelphia Chromosome Positive

M.D. Anderson Cancer Center40 enrolled2 locationsNCT06308588

Recruiting

Phase 1

Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALL

Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

H. Lee Moffitt Cancer Center and Research Institute36 enrolled1 locationNCT07250087

Recruiting

Phase 1

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

B-cell Acute Lymphoblastic LeukemiaChronic Myeloid Leukemia (CML) in Lymphoid Blast CrisisPhiladelphia Chromosome Positive Acute Lymphoblastic Leukemia Ph+ ALL

Marlise Luskin, MD40 enrolled4 locationsNCT03595917