Piriformis Syndrome Clinical Trials

10 recruitingLast updated: May 13, 2026

There are 10 actively recruiting piriformis syndrome clinical trials across 3 countries. Studies span Not Applicable. Top locations include Rawalpindi, Punjab Province, Pakistan, Islamabad, Pakistan, Islamabad, Punjab Province, Pakistan. Updated daily from ClinicalTrials.gov.


Piriformis Syndrome Trials at a Glance

10 actively recruiting trials for piriformis syndrome are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Not Applicable with 9 trials, with the heaviest enrollment activity in Rawalpindi, Islamabad, and Islamabad. Lead sponsors running piriformis syndrome studies include Foundation University Islamabad, Riphah International University, and Loma Linda University.

Browse piriformis syndrome trials by phase

Treatments under study

About Piriformis Syndrome Clinical Trials

Looking for clinical trials for Piriformis Syndrome? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Piriformis Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Piriformis Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Not Applicable

Strain-Counterstrain Treatment of Piriformis Pain

Piriformis SyndromeLow Back Pain, MechanicalSomatic Dysfunction of Sacral Region (Finding)
Loma Linda University30 enrolled1 locationNCT05023005
Recruiting
Not Applicable

Comparative Effects Of Post Isometric Relaxation Versus Active Isolated Stretch In Patients With Piriformis Syndrome

Low Back PainPiriformis SyndromeHip Joint
Foundation University Islamabad40 enrolled1 locationNCT07526012
Recruiting
Not Applicable

Instrument-Assisted Soft Tissue Mobilization Versus PNF Stretching in Athletes With Piriformis Syndrome

Piriformis Syndrome
Riphah International University40 enrolled1 locationNCT07090356
Recruiting
Not Applicable

Effects of Facilitated Positional Release Technique ( FPRT) Vs Manual Myofascial Release Technique in Female Patients With Piriformis Syndrome.

Piriformis Syndrome
Foundation University Islamabad38 enrolled1 locationNCT07044869
Recruiting

Chronic Pelvic Pain in Females and Males

Inguinal HerniaPelvic Pain SyndromePiriformis Syndrome+2 more
Salem Anaesthesia Pain Clinic1,000 enrolled1 locationNCT06102733
Recruiting
Not Applicable

"Effects of Facilitated Positional Release Technique( FPRT) Vs. Manual Myofascial Release Technique in Female Patients With Piriformis Syndrome

Piriformis Syndrome
Foundation University Islamabad38 enrolled1 locationNCT06753487
Recruiting
Not Applicable

Effects of Reciprocal Inhibition Versus Post Facilitation Muscle Energy Technique Along With Conventional Physical Therapy in Patients With Piriformis Syndrome: a Randomized Controlled Trial

Piriformis Syndrome
Foundation University Islamabad44 enrolled1 locationNCT06534788
Recruiting
Not Applicable

Comparasion of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques (METS) in Piriformis Syndrome

Piriformis Syndrome
Riphah International University32 enrolled1 locationNCT06460675
Recruiting
Not Applicable

Comparison of Effectiveness Between Active Release Technique and Hold Relax Technique in Patients With Piriformis Syndrome

Piriformis Syndrome
Foundation University Islamabad40 enrolled1 locationNCT06437327
Recruiting
Not Applicable

Effectiveness of Instrument Assisted Soft Tissue Mobilization in Management of Piriformis Syndrome

Piriformis Syndrome
Riphah International University38 enrolled1 locationNCT06406023