Low Back Pain Clinical Trials

137 recruiting

Low Back Pain Trials at a Glance

173 actively recruiting trials for low back pain are listed on ClinicalTrialsFinder across 6 cities in 31 countries. The largest study group is Not Applicable with 120 trials, with the heaviest enrollment activity in Lahore, Salt Lake City, and Leuven. Lead sponsors running low back pain studies include Riphah International University, Foundation University Islamabad, and University of Utah.

Browse low back pain trials by phase

Treatments under study

About Low Back Pain Clinical Trials

Looking for clinical trials for Low Back Pain? There are currently 137 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Low Back Pain trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Low Back Pain clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 173 trials

Recruiting
Not Applicable

Telerehabilitation-based Exercises vs Standard Home-based Exercise in Low Back Pain

Low Back Pain
University of Valencia30 enrolled1 locationNCT06446596
Recruiting
Not Applicable

Dry Needlig Vesus Tecartherapy in Low-back Pain Treatment

Low Back Pain
University of Alcala60 enrolled1 locationNCT05422040
Recruiting
Not Applicable

A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain

Low Back Pain, Chronic
Montefiore Medical Center110 enrolled1 locationNCT07214844
Recruiting
Not Applicable

Strain-Counterstrain Treatment of Piriformis Pain

Piriformis SyndromeLow Back Pain, MechanicalSomatic Dysfunction of Sacral Region (Finding)
Loma Linda University30 enrolled1 locationNCT05023005
Recruiting

Medical Record, Physical and Neurological Data That Orient to the Diagnosis of Sacroiliac Joint Dysfunction

Low Back PainSacroiliac Joint Somatic Dysfunction
University of Valencia140 enrolled1 locationNCT04381208
Recruiting
Not Applicable

Reformer Pilates vs Conventional Physiotherapy in Chronic Low Back Pain

Low Back Pain
Uskudar University36 enrolled1 locationNCT07543952
Recruiting
Phase 3

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

Chronic Low Back Pain (CLBP)ObesityOverweight
Eli Lilly and Company586 enrolled41 locationsNCT07035093
Recruiting
Not Applicable

Assessing the Japet.W+ Lumbar Traction Device in Rehabilitation for Patients With Non-specific Mechanical Low Back Pain

Low Back Pain, Mechanical
Grand Hôpital de Charleroi60 enrolled1 locationNCT06718348
Recruiting

Examination of Nociscan Impact on Discogenic Low Back Pain Surgical Outcomes

Discogenic Low Back Pain
Aclarion300 enrolled8 locationsNCT06661850
Recruiting
Not Applicable

Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

Chronic Low-back PainChronic PainLow Back Pain+1 more
Boston Scientific Corporation70 enrolled7 locationsNCT07190807
Recruiting
Not Applicable

Placebo-Induced Hypoalgesia During Transcutaneous Electrical Nerve Stimulation Application in Low Back Pain

Low Back PainLow Back Pain (LBP)
Cairo University40 enrolled1 locationNCT07535047
Recruiting
Phase 4

Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.

Low Back PainRadiculopathy, Lumbosacral RegionBack Pain With Radiation
Montefiore Medical Center132 enrolled2 locationsNCT05721027
Recruiting

GLA:D Back Canada - a Program for Chronic and Persistent Low Back Pain

Low Back Pain
University of Alberta2,200 enrolled1 locationNCT06924671
Recruiting
Not Applicable

Comparative Effects Of Post Isometric Relaxation Versus Active Isolated Stretch In Patients With Piriformis Syndrome

Low Back PainPiriformis SyndromeHip Joint
Foundation University Islamabad40 enrolled1 locationNCT07526012
Recruiting
Not Applicable

Pain Education and Patient-led Goal Setting in Adults With Chronic Low Back Pain: a Randomised Controlled Trial

Chronic Low Back Pain (Non-specific, Uncomplicated)
Neuroscience Research Australia392 enrolled1 locationNCT06620133
Recruiting
Not Applicable

Effects of Lumbar Stabilization Exercises Versus Muscular Chain Therapy in Patients With Mechanical Chronic Low Back Pain

Low Back Pain, Mechanical
Ibadat International University, Islamabad42 enrolled1 locationNCT07523906
Recruiting
Not Applicable

Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome

Low Back Pain
University of Rzeszow110 enrolled1 locationNCT07463729
Recruiting
Not Applicable

The Long Term Effects of Online Therapeutic Neuroscience Education in Patients With Chronic Low Back Pain

Chronic PainLow Back Pain, Mechanical
Istanbul Bilgi University60 enrolled1 locationNCT06847763
Recruiting

Impact of Low Back Pain Phenotypes on Function and Quality of Life in Ankylosing Spondylitis

Ankylosing SpondylitisLow Back Pain
Konya Beyhekim Training and Research Hospital200 enrolled1 locationNCT07510789
Recruiting
Not Applicable

Comparative Effects of Cognitive Functional Therapy With Kinetic Control Training on Non-specific Low Back Pain

Low Back Pain
Lahore University of Biological and Applied Sciences70 enrolled1 locationNCT07282925