Popliteal Clinical Trials

15 recruitingLast updated: May 13, 2026

There are 15 actively recruiting popliteal clinical trials across 14 countries. Studies span Not Applicable, Early Phase 1. Top locations include Sydney, Australia, New York, New York, United States, Melbourne, Australia. Updated daily from ClinicalTrials.gov.


Popliteal Trials at a Glance

15 actively recruiting trials for popliteal are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 11 trials, with the heaviest enrollment activity in Sydney, New York, and Melbourne. Lead sponsors running popliteal studies include Balton Sp.zo.o., Biotyx Medical (Shenzhen) Co., Ltd., and Ain Shams University.

Browse popliteal trials by phase

About Popliteal Clinical Trials

Looking for clinical trials for Popliteal? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Popliteal trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Popliteal clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Not Applicable

The Efemoral Vascular Scaffold System (EVSS) for the Treatment of Patients With Symptomatic Peripheral Vascular Disease From Stenosis or Occlusion of the Femoropopliteal Artery

Peripheral Arterial DiseaseStenosisVascular Diseases+1 more
Efemoral Medical, Inc.100 enrolled8 locationsNCT04584632
Recruiting

Evaluation of the Clinical Outcomes of the Embolic Protection System in Preventing Distal Embolism During Femoropopliteal Debulking Procedures

Femoropopliteal Disease
RenJi Hospital150 enrolled1 locationNCT07282301
Recruiting
Not Applicable

First In Human Study to Assess Safety and Efficacy of the ChampioNIR™ Drug Eluting Peripheral Stent in the Treatment of Patients With Superficial Femoral Artery Disease and/or Proximal Popliteal Artery Disease

Superficial Femoral Artery StenosisPopliteal Artery Stenosis
Medinol Ltd.30 enrolled7 locationsNCT06410313
Recruiting

Assessing the Enhanced Precision: The Value of Impedance in Ultrasound-Guided Nerve Blocks (Axillary, Interscalene, Popliteal Sciatic), an Exploratory Prospective Observational Study

ImpedanceAxillary Nerve BlockUltrasound-Guided Nerve Blocks+2 more
Lebanese American University100 enrolled1 locationNCT06620471
Recruiting
Not Applicable

The Immediate Effect of Applying Transcutaneous Electrical Nerve Stimulation (TENS) on Sympathetic Ganglion and Gastrocnemius for Popliteal Blood Flow

Transcutaneous Electrical Nerve Stimulation (TENS)PoplitealBlood Flow+1 more
Kaohsiung Medical University43 enrolled1 locationNCT06882733
Recruiting
Not Applicable

Revascularization of Single Vesrus Multiple Infrapopliteal Vessels in Chronic Limb Threatening Ischemia

Chronic Limb Threatening IschemiaInfrapopliteal Arterial Occlusive Disease
Sohag University40 enrolled1 locationNCT07068789
Recruiting

The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)

Peripheral Arterial DiseaseSymptomatic Femoropopliteal Lesions
Endologix450 enrolled10 locationsNCT06315023
Recruiting
Not Applicable

Combination Therapy of Atherectomy Plus Drug-coated Balloon Versus Drug-coated Balloon for Complex Femoropopliteal Artery Disease

Femoropopliteal Artery Disease
Yonsei University300 enrolled1 locationNCT05307263
Recruiting
Not Applicable

Histological Segmentation of the Superficial Femoral Artery From Microscan to CT Using Artificial Intelligence

Peripheral Artery DiseaseFemoropopliteal Stenosis
University Hospital, Strasbourg, France20 enrolled1 locationNCT06260488
Recruiting
Not Applicable

Effect of Continuous Adductor Canal Block Versus Continuous Adductor Canal Block With Additional Infiltration Between The Popliteal Artery and Capsule of The Knee (IPACK) After Arthroscopic Knee Surgeries

Continuous Adductor Canal BlockInfiltration Between The Popliteal Artery and Capsule of The KneeArthroscopic Knee Surgeries
Ain Shams University70 enrolled1 locationNCT06802419
Recruiting
Not Applicable

STAR-PAK Study: Evaluating the Safety and Efficacy of PAK® (Paclitaxel Coated Balloon) in Treating Atherosclerotic Femoro-Popliteal Lesions

Peripheral Artery DiseaseSuperficial Femoral Artery StenosisPopliteal Artery Stenosis Above the Knee
Balton Sp.zo.o.120 enrolled3 locationsNCT06734221
Recruiting
Not Applicable

FRAMED Infrainguinal Venous Bypass Versus Conventional Autologous Bypass Trial

Peripheral arterial occlusive diseaseFemoropopliteal StenosisClaudication, Intermittent+2 more
Paracelsus Medical University110 enrolled1 locationNCT06082466
Recruiting
Not Applicable

IBS Titan™ Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System Clinical Trial

Infrapopliteal LesionsCritical Limb Ischemia
Biotyx Medical (Shenzhen) Co., Ltd.100 enrolled1 locationNCT05971394
Recruiting
Not Applicable

Prospective Case-control Study in Patients With PAA

Quality of LifePeripheral Arterial DiseasePopliteal Artery Aneurysm
Rebecka Hultgren130 enrolled2 locationsNCT04188808
Recruiting
Early Phase 1

The Tetherx Natural Vascular Scaffolding (NVS) Procedure for Treating Patients with Atherosclerosis of the Femoropopliteal Artery

Symptoms of claudication or ischemic rest pain (Rutherford category 2, 3, or 4) with suspected atherosclerosis in either the superficial femoral artery or the proximal popliteal artery (above the knee articulation).
Tetherx, Inc.30 enrolled1 locationACTRN12611000897965