Post-surgical pain Clinical Trials

12 recruitingLast updated: July 25, 2026

There are 12 actively recruiting post-surgical pain clinical trials across 9 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Boston, Massachusetts, United States, Cairo, Cairo Governorate, Egypt, Dalin, Chai-Yi, Taiwan. Updated daily from ClinicalTrials.gov.


Post-surgical pain Trials at a Glance

12 actively recruiting trials for post-surgical pain are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Boston, Cairo, and Dalin. Lead sponsors running post-surgical pain studies include Cairo University, Chantel Burkitt, and Brigham and Women's Hospital.

Browse post-surgical pain trials by phase

Treatments under study

About Post-surgical pain Clinical Trials

Looking for clinical trials for Post-surgical pain? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Post-surgical pain trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Post-surgical pain clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

HONEY for the Treatment of POst-Tonsillectomy Pain

Post-surgical painAnalgesia
East and North Hertfordshire NHS Trust100 enrolled1 locationNCT06275698
Recruiting
Not Applicable

Effectiveness of Perioperative Percutaneous Acupuncture on Postoperative Sleep Disturbances and Chronic Pain in Patients Undergoing Video-Assisted Thoracoscopic Lung Cancer Resection: A Prospective, Randomized, Single-Blind, Superiority Controlled Trial

Chronic post-surgical painPostoperative Sleep Disturbances
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine316 enrolled2 locationsNCT07662733
Recruiting
Not Applicable

Yoga for Persistent Post-Surgical Pain (PPSP)

Persistent Post-surgical Pain
Brigham and Women's Hospital50 enrolled1 locationNCT06949007
Recruiting
Not Applicable

Surgical COrncerns and Psychological Evaluation of Patients Undergoing Elective Surgery

Elective surgeryAnxietyChronic post-surgical pain
University Hospital, Antwerp30 enrolled1 locationNCT07158684
Recruiting
Not Applicable

Ultrasound-Guided SPSIP Versus ESPB for Postoperative Pain After Modified Radical Mastectomy

Breast CancerPostoperative PainAcute Post-surgical Pain
Cairo University50 enrolled1 locationNCT07446868
Recruiting
Not Applicable

Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.

Chronic Knee PainChronic post-surgical painChronic post operative pain
Consorci Sanitari de l'Alt Penedès i Garraf86 enrolled1 locationNCT05920382
Recruiting
Not Applicable

Psychophysical and Neural Mechanisms Contributing to Chronic Post-Surgical Pain in Adolescents and Adults

Chronic post-surgical pain
Massachusetts General Hospital110 enrolled1 locationNCT05304286
Recruiting
Not Applicable

Uncovering the Mechanism of Pain Relief by Peripheral Transcutaneous Magnetic Stimulation

Post-Surgical Pain, ChronicPost-traumatic Pain, Chronic
Florida International University50 enrolled1 locationNCT07199361
Recruiting

Chronic Postsurgical Pain

Cerebral PalsyChronic post-surgical pain
Chantel Burkitt500 enrolled2 locationsNCT05764681
Recruiting
Phase 2Phase 3

Dinalbuphine Ester (Naldebain) for Pain Management After Cesarean Section

postsurgical painCesarean SectionChronic post-surgical pain
Dalin Tzu Chi General Hospital120 enrolled1 locationNCT06344169
Recruiting

Chronic Postsurgical Pain: Multivariate Prediction Model

Post-surgical painPost Operative PainPostoperative Pain, Chronic
Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva1,500 enrolled1 locationNCT06417528
Recruiting

Can virtual reality help people to manage their pain after surgery? A pilot study

Post-surgical pain
St Vincent's Hospital Sydney80 enrolled1 locationACTRN12620000222943